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用于预测择期腹部手术患者诱导后低血压的颈动脉校正血流时间和多普勒休克指数:一项前瞻性观察研究。

Carotid corrected flow time and Doppler shock index for prediction of post-induction hypotension in patients undergoing elective abdominal surgery: a prospective observational study.

作者信息

Sun Tao, Hui Kangli, Ren Liwen, Han Mengtong, Shen Xiaoyun, Xiong Jingwei, Qi Hongwei, Duan Manlin

机构信息

Department of Anesthesiology, Affiliated Hospital of Medical School, Nanjing Jinling Hospital, Nanjing University, Zhongshan East Road #305, Nanjing, 210002, China.

Department of Anesthesiology, Nanjing Tianyinshan Hospital, the First Affiliated Hospital of China Pharmaceutical University, Nanjing, China.

出版信息

Perioper Med (Lond). 2025 Mar 29;14(1):38. doi: 10.1186/s13741-025-00519-7.

DOI:10.1186/s13741-025-00519-7
PMID:40156069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11954297/
Abstract

BACKGROUND

Abdominal surgical patients who have deficient blood volume are at an elevated risk of post-induction hypotension (PIH). New strategies have been adopted, i.e., carotid ultrasound, to evaluate volume status. The study aimed to investigate and compare the predictive value of various carotid ultrasound parameters for PIH.

METHODS

Adult patients scheduled for abdominal surgery were enrolled. Carotid ultrasound was performed before induction to evaluate the carotid flow time (FT), carotid artery velocity time integral (VTI), and Doppler shock index (the DSI and DSI). Both Wodey's (W) and Bazett's (B) formulae determined the corrected flow time (FTc). The predictive ability of these parameters was analyzed via receiver operating characteristic (ROC) curve analysis.

RESULTS

Finally, 94 patients were analyzed, and of those, 40 (42.6%) developed PIH. The areas under the curve for FT, FTc(W), 1/DSI, and FTc(B) were 0.790 (95% CI 0.697-0.883) (P < 0.05), 0.788 (95% CI 0.695-0.881) (P < 0.001), 0.729 (95% CI 0.626-0.832) (P < 0.001), and 0.689 (95% CI 0.582-0.796) (P < 0.05), respectively. The optimal cut-off for FTc(W) was 334.15 ms (sensitivity 82.5%, specificity 70.4%), while for FT, it was 313.33 ms (sensitivity 72.5%, specificity 79.6%), indicating FTc(W) as the best predictor among these various parameters. The 1/DSI was an inferior predictor of PIH, with an optimal cutoff value of 4.58. The sensitivity (80.0%) and specificity (61.1%) values were obtained.

CONCLUSION

Carotid flow time corrected by Wodey's formula was a reliable indicator of PIH in patients undergoing elective abdominal surgery, superior to FT, DSI, and FTc(B).

摘要

背景

血容量不足的腹部外科手术患者诱导后低血压(PIH)风险升高。已采用新策略,即颈动脉超声,来评估容量状态。本研究旨在调查和比较各种颈动脉超声参数对PIH的预测价值。

方法

纳入计划接受腹部手术的成年患者。诱导前进行颈动脉超声检查,以评估颈动脉血流时间(FT)、颈动脉速度时间积分(VTI)和多普勒休克指数(DSI)。Wodey公式(W)和Bazett公式(B)均用于确定校正血流时间(FTc)。通过受试者工作特征(ROC)曲线分析来分析这些参数的预测能力。

结果

最终分析了94例患者,其中40例(42.6%)发生了PIH。FT、FTc(W)、1/DSI和FTc(B)的曲线下面积分别为0.790(95%CI 0.697 - 0.883)(P < 0.05)、0.788(95%CI 0.695 - 0.881)(P < 0.001)、0.729(95%CI 0.626 - 0.832)(P < 0.001)和0.689(95%CI 0.582 - 0.796)(P < 故灵敏度(80.0%)和特异性(61.1%)。

结论

Wodey公式校正的颈动脉血流时间是择期腹部手术患者PIH的可靠指标,优于FT、DSI和FTc(B)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc14/11954297/14eac946262e/13741_2025_519_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc14/11954297/a3b1ae80f887/13741_2025_519_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc14/11954297/433ef6186aee/13741_2025_519_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc14/11954297/b4c45d4af51b/13741_2025_519_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc14/11954297/14eac946262e/13741_2025_519_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc14/11954297/a3b1ae80f887/13741_2025_519_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc14/11954297/433ef6186aee/13741_2025_519_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc14/11954297/b4c45d4af51b/13741_2025_519_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc14/11954297/14eac946262e/13741_2025_519_Fig4_HTML.jpg

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