Wang Zuxing, Ye Yu, Dou Yikai, Chen Lili, Zou Zhili
Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Soc Sci Med. 2025 May;373:117962. doi: 10.1016/j.socscimed.2025.117962. Epub 2025 Mar 14.
Self-harm and interpersonal violence are pressing global public health concerns, with high alcohol consumption being a significant contributing factor. This study analyzes global trends of self-harm and interpersonal violence attributable to high alcohol use from 1990 to 2021, including the impact of the COVID-19 pandemic.
Age-standardized death rates (ASDR) and disability-adjusted life years (DALYs) were extracted from the Global Burden of Disease (GBD) 2021 to explore the trends of burden. Data were categorized by gender, age groups, regions, and countries, each with a 95 % uncertainty interval (UI). Bayesian age-period-cohort (BAPC) models were used to forecast future trends.
In 2021, the global ASDR for self-harm and interpersonal violence attributable to high alcohol use was 0.84 (95 % uncertainty interval [UI]: 0.37 to 1.33) and 0.40 (95 % UI: 0.23 to 0.59) per 100,000 population, respectively. Males had consistently higher ASDRs and DALYs than females across all age groups, particularly in the 20-39 age range, where deaths and DALYs peaked for both outcomes. Regionally, Eastern Europe had the highest burden of self-harm, while Central Latin America showed the highest rates of interpersonal violence attributable to high alcohol use. By 2035, ASDR is projected to decrease by 17 % and 21 % for self-harm and interpersonal violence, respectively.
Global alcohol-related self-harm and violence declined long-term but stalled during COVID-19, with higher burdens among males and specific age groups, and significant regional disparities. Sustained public health efforts, targeted policies, and innovative interventions are essential to address persistent disparities and future challenges.
自我伤害和人际暴力是紧迫的全球公共卫生问题,高酒精消费是一个重要促成因素。本研究分析了1990年至2021年因高酒精使用导致的自我伤害和人际暴力的全球趋势,包括新冠疫情的影响。
从《2021年全球疾病负担》(GBD 2021)中提取年龄标准化死亡率(ASDR)和伤残调整生命年(DALY),以探究负担趋势。数据按性别、年龄组、地区和国家分类,每个类别都有95%的不确定性区间(UI)。使用贝叶斯年龄-时期-队列(BAPC)模型预测未来趋势。
2021年,因高酒精使用导致的自我伤害和人际暴力的全球ASDR分别为每10万人0.84(95%不确定性区间[UI]:0.37至1.33)和0.40(95% UI:0.23至0.59)。在所有年龄组中,男性的ASDR和DALY一直高于女性,特别是在20-39岁年龄范围内,这两个结果的死亡人数和DALY均达到峰值。在区域方面,东欧的自我伤害负担最高,而中美洲拉丁地区因高酒精使用导致的人际暴力发生率最高。预计到2035年,自我伤害和人际暴力的ASDR将分别下降17%和21%。
全球与酒精相关的自我伤害和暴力长期呈下降趋势,但在新冠疫情期间停滞,男性和特定年龄组的负担更高,且存在显著的地区差异。持续的公共卫生努力、针对性政策和创新干预措施对于解决持续存在的差异和未来挑战至关重要。