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探索针刺镇痛的空间效应。

Exploring the spatial effects of acupuncture analgesia.

作者信息

Wang Zihe, Qin Peng, Chen Yuyan, Cheng Yupei, Liu Longxiao, Zhang Yuxing, Wu Bangqi

机构信息

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China; Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China.

出版信息

Neuroscience. 2025 May 7;573:300-314. doi: 10.1016/j.neuroscience.2025.03.053. Epub 2025 Mar 28.

Abstract

In recent years, researchers have conducted in-depth research on the mechanism of acupuncture analgesia and made many important discoveries. These studies indicate that acupuncture can effectively alleviate pain and improve pain mood. This article summarizes the mechanisms of acupuncture treatment for different types of pain, including peripheral input effects, spinal cord response effects, and brain integration effects. It provides support for the idea that acupuncture analgesia is not a local reaction through a single pathway, but a holistic effect with network connections. However, it is unclear whether the peripheral, spinal cord, and brain levels have equal analgesic effects during the analgesic process, or which level dominates the analgesic effect; The issue of whether the dominant analgesic level is consistent for different types of pain has not been resolved and further experimental research is needed.

摘要

近年来,研究人员对针刺镇痛机制进行了深入研究,并取得了许多重要发现。这些研究表明,针刺能有效缓解疼痛并改善疼痛情绪。本文总结了针刺治疗不同类型疼痛的机制,包括外周输入效应、脊髓反应效应和脑整合效应。它为针刺镇痛不是通过单一途径的局部反应,而是具有网络连接的整体效应这一观点提供了支持。然而,在镇痛过程中外周、脊髓和脑水平是否具有同等的镇痛作用,或者哪个水平主导镇痛作用尚不清楚;不同类型疼痛的主导镇痛水平是否一致的问题也尚未解决,需要进一步的实验研究。

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