STAR试验标准以外患者的舌下神经刺激：一项系统评价
Hypoglossal nerve stimulation in patients outside the STAR trial criteria: a systematic review.
作者信息
Tze Xin Pamela Lim, Gui Chuan Hao, Tan Soon Heng Terry
机构信息
Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Department of Otorhinolaryngology, Woodlands Health, Singapore.
出版信息
J Laryngol Otol. 2025 Mar 31;139(7):1-11. doi: 10.1017/S0022215125000295.
OBJECTIVES
This study aimed to evaluate if there is a role for hypoglossal nerve stimulation outside the original Stimulation Therapy for Apnea Reduction (STAR) trial criteria.
METHODS
This review was conducted using PubMed, Embase and Cochrane Library databases.
RESULTS
Hypoglossal nerve stimulation led to improved outcomes in individuals who fell outside the STAR trial criteria for apnoea-hypopnoea index and body mass index. However, this improvement did not extend to patients with complete concentric palatal collapse or those with a significant central apnoea component.
CONCLUSION
Hypoglossal nerve stimulation can be effective in patients outside the original STAR trial criteria for certain parameters. Further research is needed to refine patient selection criteria for optimal outcomes.
目的
本研究旨在评估在原有的减少呼吸暂停刺激疗法（STAR）试验标准之外，舌下神经刺激是否起作用。
方法
本综述通过使用PubMed、Embase和Cochrane图书馆数据库进行。
结果
对于呼吸暂停低通气指数和体重指数不符合STAR试验标准的个体，舌下神经刺激可改善其预后。然而，这种改善并未扩展至完全同心性腭塌陷患者或具有显著中枢性呼吸暂停成分的患者。
结论
对于某些参数，舌下神经刺激在不符合原STAR试验标准的患者中可能有效。需要进一步研究以完善患者选择标准，从而获得最佳预后。
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