Advances in the structural characterization and pharmacological activity of Salvia miltiorrhiza polysaccharides.

BACKGROUND

Bunge is the dried root and rhizome of Bunge, a labiatae plant. polysaccharide (SMP) is the main active component of Bunge. The extraction methods of SMP mainly include water extraction, ultrasonic extraction, enzyme extraction, microwave-assisted extraction and acid-base extraction. It is mainly composed of glucose, arabinose, rhamnose, galactose and other monosaccharides. SMP has a variety of biological activities, including immune regulation, anti-tum, anti-oxidation, myocardial protection, liver protection and so on.

PURPOSE

polysaccharide is widely used in nutraceuticals and pharmaceuticals, and has high research value. Natural polysaccharides are non-toxic, soluble in water, and have a wide range of biological activities, so they have broad research prospects.

METHODS

The data was collected using different online resources including PubMed, Google Scholar, and Web of Science using keywords given below.

RESULTS

In the past decades, various reports have shown that the pharmacological activities of polysaccharides have good effects, and the side effects are small.

CONCLUSION

This paper summarizes the extraction and purification methods, molecular weight, monosaccharide composition, glycosidic linkage, pharmacological activity, toxicity, product development, clinical research and other contents of polysaccharides in recent years, providing a theoretical basis for further study of polysaccharides.