Rawal Rushil, Davood Joshua, Heard John, Castaneda Peris, Kim Hyung, Luthringer Daniel, Ahdoot Michael
Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Urol Case Rep. 2025 Mar 7;60:102994. doi: 10.1016/j.eucr.2025.102994. eCollection 2025 May.
A 74-year-old man with PSA of 21.1 ng/mL, eGFR of 13 mL/min/1.73 m (stage 4 renal disease), and an 889 mL prostate (MRI; transrectal ultrasound estimated 1000 mL) underwent robotic simple prostatectomy for severe lower urinary tract symptoms, including nocturia and recurrent urinary retention. Adenoma dissection, bladder re-anastomosis, and morcellation resulted in 500 mL blood loss and one transfusion. Pathology revealed stromal/glandular hyperplasia and incidental Gleason 8 (3 + 5) adenocarcinoma (<2 % of tissue, no invasion). At six months, PSA was 0.25 ng/mL, with good continence. This case highlights successful robotic management of massive BPH with incidental malignancy.
一名74岁男性,前列腺特异性抗原(PSA)为21.1 ng/mL,估算肾小球滤过率(eGFR)为13 mL/min/1.73 m²(4期肾病),前列腺体积为889 mL(磁共振成像[MRI];经直肠超声估计为1000 mL),因严重下尿路症状,包括夜尿症和反复尿潴留,接受了机器人辅助单纯前列腺切除术。腺瘤剥离、膀胱重新吻合和粉碎术导致失血500 mL,接受了一次输血。病理检查显示为间质/腺性增生,偶然发现Gleason 8(3+5)腺癌(占组织不到2%,无浸润)。术后6个月时,PSA为0.25 ng/mL,控尿良好。该病例突出了对合并恶性肿瘤的巨大良性前列腺增生症成功进行机器人手术治疗的情况。