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早期营养干预在肝癌肝移植患者中的应用进展

Application progress of early nutrition intervention in patients with hepatocellular carcinoma after liver transplantation.

作者信息

Deng Shan-Shan, Zhu Yu-Ping, Chen Zhi-Tao, Li Wan

机构信息

Department of Medical Oncology, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International, Medical College, Hangzhou 310022, Zhejiang Province, China.

Department of Hepatobiliary Pancreatic Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International, Medical College, Hangzhou 310022, Zhejiang Province, China.

出版信息

World J Gastrointest Surg. 2025 Mar 27;17(3):100321. doi: 10.4240/wjgs.v17.i3.100321.

Abstract

Liver transplantation, as an effective therapy for patients with liver cancer, plays an important role in improving the quality of life of patients. However, the complexity and trauma of liver transplantation can easily lead to the occurrence of malnutrition in patients, and then increase the risk of postoperative complications, which has aroused widespread clinical attention. Reasonable nutritional support can not only maintain the stability of the body's internal environment, reduce the occurrence of complications, but also promote the recovery of liver and other organ functions. In recent years, with the in-depth understanding of nutritional metabolism after liver transplantation, the application of enteral nutrition and parenteral nutrition in nutritional support after liver transplantation has been increasingly extensive and achieved remarkable results. This paper discusses the effect of early postoperative nutritional intervention on patients with liver cancer and liver transplantation, and combined with its mechanism of action, can better understand the effectiveness of intervention, and provide reference for the development of scientific and reasonable nutritional support programs in clinical practice.

摘要

肝移植作为肝癌患者的一种有效治疗方法,在改善患者生活质量方面发挥着重要作用。然而,肝移植的复杂性和创伤性容易导致患者发生营养不良,进而增加术后并发症的风险,这已引起临床广泛关注。合理的营养支持不仅可以维持机体内部环境的稳定,减少并发症的发生,还能促进肝脏及其他器官功能的恢复。近年来,随着对肝移植后营养代谢认识的深入,肠内营养和肠外营养在肝移植后营养支持中的应用越来越广泛,并取得了显著成效。本文探讨了术后早期营养干预对肝癌肝移植患者的影响,并结合其作用机制,能更好地了解干预的有效性,为临床实践中制定科学合理的营养支持方案提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f04f/11948105/489f0ca9d1d7/100321-g001.jpg

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