Gerena Rolando G, Asamoah Philip, Loftis Christine E, Caplan Liron, Merkle Alexander N
Department of Radiology, Division of Musculoskeletal Imaging and Intervention, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Department of Radiology, Division of Musculoskeletal Imaging and Intervention, Massachusetts General Hospital, Boston, Massachusetts.
Semin Musculoskelet Radiol. 2025 Apr;29(2):196-209. doi: 10.1055/s-0045-1802651. Epub 2025 Mar 31.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease primarily affecting the axial skeleton, historically termed "human leukocyte antigen B27 positive spondyloarthropathy" or ankylosing spondylitis. Improved understanding of the underlying pathologic mechanisms has led to an ongoing redefinition of this disease state, a recognition of the substantial phenotypic and biological variation, and an emphasis on earlier detection. Magnetic resonance imaging has become central to identifying and confirming early axSpA, critical to fulfilling the promise of slowing disease progression and preventing irreversible structural abnormalities. We review the clinical background and current role of medical imaging in axSpA, with a focus on Assessment of SpondyloArthritis International Society consensus definitions, to improve radiology reporting and facilitate discussion between radiologists and other clinical experts in spondyloarthritis.
轴性脊柱关节炎（axSpA）是一种主要影响中轴骨骼的慢性炎症性疾病，过去被称为“人类白细胞抗原B27阳性脊柱关节病”或强直性脊柱炎。对潜在病理机制的深入理解促使对这种疾病状态进行持续重新定义，认识到其显著的表型和生物学差异，并强调早期检测。磁共振成像已成为识别和确诊早期axSpA的核心手段，对于实现减缓疾病进展和预防不可逆结构异常的目标至关重要。我们回顾了axSpA的临床背景以及医学成像的当前作用，重点关注国际脊柱关节炎评估协会的共识定义，以改进放射学报告并促进放射科医生与脊柱关节炎其他临床专家之间的讨论。
