Pedlar J
Br J Plast Surg. 1985 Jul;38(3):347-51. doi: 10.1016/0007-1226(85)90240-1.
Healing was observed for 6 months following excision of full thickness normal adult human palatal mucosa (approx 12 mm X 10 mm) to measure the degree of wound contraction and determine if rugae would regenerate. Measurements of plaster models showed stretching and displacement of soft tissue not involved in the original would toward the centre of the wound from 6 weeks postoperatively. The distance between the incisive papilla and the most posterior ruga on the side of operation reduced by 2.2 mm and the first ruga on the opposite side was stretched in length by 0.9 mm. A fragment of superficial bone (approx 10 mm X 7 mm) sequestrated at 5 weeks, epithelialisation was complete by 8 weeks but the rugae did not reform at all.
在切除成年正常人全层腭黏膜（约12毫米×10毫米）后观察愈合情况6个月，以测量伤口收缩程度并确定皱襞是否会再生。石膏模型测量显示，术后6周起，未参与原始伤口的软组织向伤口中心拉伸和移位。手术侧切牙乳头与最靠后的皱襞之间的距离减少了2.2毫米，对侧的第一条皱襞长度拉伸了0.9毫米。5周时出现一块浅表骨碎片（约10毫米×7毫米），8周时上皮化完成，但皱襞完全未重新形成。
