Larson C T, Gross W B, Davis J W
Can J Comp Med. 1985 Apr;49(2):208-10.
The purpose of this research was to determine the effect of social stress on the susceptibility of chickens and swine to Staphylococcus aureus infection. Chickens were housed under four levels of social stress. Weaned pigs remained with their litter or were housed separately. One day after some birds were placed in the high stressed environments all were challenged intravenously with S. aureus. Susceptibility was characterized by joint infection in swine and reduced weight gain in chickens. Chickens which were moved into the high stressed environments before challenge lost weight while the controls gained weight (P less than 0.001). During the three days postchallenge the most severely stressed chickens lost less than half as much body weight as did the least stressed (P less than 0.001). During the post-challenge period chickens selected for high corticosterone response in a high social stress gained weight while chickens selected for a low corticosterone response in a low stress environment lost weight (P less than 0.0001). Swine housed under a reduced level of stress (social) were more susceptible to S. aureus than those kept under higher levels of stress (P = 0.0001).
本研究的目的是确定社会应激对鸡和猪感染金黄色葡萄球菌易感性的影响。将鸡饲养在四种社会应激水平下。断奶仔猪与同窝仔猪一起饲养或单独饲养。在将一些鸡置于高应激环境一天后，所有鸡均通过静脉注射金黄色葡萄球菌进行攻毒。易感性的特征是猪发生关节感染以及鸡体重增加减少。在攻毒前被转移到高应激环境中的鸡体重减轻，而对照组体重增加（P<0.001）。在攻毒后的三天内，应激最严重的鸡体重减轻不到应激最轻的鸡的一半（P<0.001）。在攻毒后期间，在高社会应激中被选择具有高皮质酮反应的鸡体重增加，而在低应激环境中被选择具有低皮质酮反应的鸡体重减轻（P<0.0001）。处于较低应激水平（社会应激）下的猪比处于较高应激水平下的猪更容易感染金黄色葡萄球菌（P = 0.0001）。
