Cotter P F, Taylor R L
Biology Department, Framingham State College, Massachusetts 01701.
Poult Sci. 1991 Jun;70(6):1357-61. doi: 10.3382/ps.0701357.
Trials were conducted to determine whether differential resistance to challenge with Staphylococcus aureus was characteristic of two related lines of New Hampshire chickens differing genetically in size of the bursa of Fabricius. Neonatal small bursa line (SBL) chicks were superior to the unselected Lester J. Dreesen (LJD) line in five of six trials employing intracardiac challenge (chi 2 = 6.3, .05 greater than P greater than .01). Older (7 to 12 wk) SBL chicks, challenged intravenously, had superior resistance than Line LJD chicks in three of four trials where a direct comparison was possible. The mortality rate in Line SBL was 34% in all trials compared with a 54% mortality rate (chi 2 = 11.7, P less than .001) in Line LJD. Moreover, the development of morbidity was more rapid in Line LJD. It is suggested that these lines can be of use in investigations of the nature of resistance to staphylococcal disease.
进行了多项试验，以确定对金黄色葡萄球菌攻击的差异抗性是否是两个在法氏囊大小上存在遗传差异的相关新罕布什尔鸡品系的特征。在六项采用心内攻击的试验中，新生小法氏囊品系（SBL）雏鸡在其中五项试验中优于未选育的莱斯特·J·德雷森（LJD）品系（卡方检验=6.3，0.05＞P＞0.01）。在四项可进行直接比较的静脉内攻击试验中，年龄较大（7至12周）的SBL品系雏鸡在其中三项试验中比LJD品系雏鸡具有更强的抗性。在所有试验中，SBL品系的死亡率为34%，而LJD品系的死亡率为54%（卡方检验=11.7，P＜0.001）。此外，LJD品系发病的发展更为迅速。建议这些品系可用于研究对葡萄球菌病抗性的本质。
