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78例难治性咽溃疡的临床分析

[Clinical analysis of 78 cases of refractory pharyngeal ulcers].

作者信息

Ma Jingyuan, Wang Guangke, Li Jing, Zang Yanzi

机构信息

Department of Otorhinolaryngology,Henan Provincial People's Hospital,Zhengzhou University People's Hospital,Zhengzhou,450003,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2025 Apr;39(4):362-367;375. doi: 10.13201/j.issn.2096-7993.2025.04.013.

Abstract

To explore the clinical characteristics, treatment methods, and prognosis of refractory pharyngeal ulcers. A retrospective analysis was conducted on the clinical manifestations, laryngoscopic features, laboratory tests, histopathological examinations, and treatments of 78 patients diagnosed with refractory pharyngeal ulcers. There was no significant difference in the proportion of males-to-females in benign lesions, while males were significantly more prevalent in cases of malignant lesions. Seven distinct pathological types of pharyngeal ulcers were identified, with the most common being simple inflammatory ulcers(18 cases), followed by tuberculosis(16 cases), fungi(15 cases), lymphoma(14 cases), squamous cell carcinoma(10 cases), Behcet's disease(3 cases), and myelosarcoma(2 cases). The clinical manifestations and lesions associated with refractory pharyngeal ulcers are diverse. A clear diagnosis should be established based on a systematic and comprehensive medical history, specialized examinations, and additional tests to avoid misdiagnosis and mistreatment. Laryngoscopy and histopathological examinations are essential for identifying the type of lesion and guiding appropriate treatment.

摘要

探讨难治性咽溃疡的临床特征、治疗方法及预后。对78例诊断为难治性咽溃疡患者的临床表现、喉镜特征、实验室检查、组织病理学检查及治疗情况进行回顾性分析。良性病变中男女比例无显著差异,而恶性病变中男性明显更为常见。共识别出7种不同病理类型的咽溃疡,最常见的是单纯性炎性溃疡(18例),其次是结核(16例)、真菌(15例)、淋巴瘤(14例)、鳞状细胞癌(10例)、白塞病(3例)和髓肉瘤(2例)。难治性咽溃疡的临床表现及病变多样。应基于系统全面的病史、专科检查及其他检查明确诊断,以避免误诊和误治。喉镜检查及组织病理学检查对于明确病变类型及指导恰当治疗至关重要。

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