Hegelmann Markus, Cokoja Mirza
Department of Chemistry and Catalysis Research Center, School of Natural Sciences, Technical University of Munich, Ernst-Otto-Fischer Straße 1, D-85748, Garching bei München, Germany.
Chempluschem. 2025 Jun;90(6):e202500122. doi: 10.1002/cplu.202500122. Epub 2025 Apr 16.
Biphasic molecular catalysis is a promising strategy for combining catalyst recycling with the synthesis of advanced chemical products. The anchoring of catalysts to surfactants in water allows for both catalyst solubility in aqueous media and a simple separation from the organic product. In biphasic epoxidations, this approach allows the use of environmentally benign hydrogen peroxide as oxidant. However, challenges remain due to mass transport limitations between the aqueous and organic phase, incompatibilities in the multicomponent system, and side reactions in the acidic medium. Hence, the development of surface-active catalysts that enable controlled phase separation from all other components is highlighted in this concept article.
双相分子催化是一种将催化剂循环利用与先进化学产品合成相结合的很有前景的策略。将催化剂锚定在水中的表面活性剂上，既可以使催化剂在水介质中溶解，又能与有机产物简单分离。在双相环氧化反应中，这种方法允许使用环境友好的过氧化氢作为氧化剂。然而，由于水相和有机相之间的传质限制、多组分体系中的不相容性以及酸性介质中的副反应，挑战依然存在。因此，在这篇概念文章中强调了开发能够与所有其他组分实现可控相分离的表面活性催化剂。
