Chira Angeliki, Kokkinos Nikolaos C
Department of Chemistry, School of Sciences, Democritus University of Thrace, Ag. Loukas, 654 04 Kavala, Greece.
Petroleum Institute, Democritus University of Thrace, Ag. Loukas, 654 04 Kavala, Greece.
Int J Mol Sci. 2025 Apr 24;26(9):4028. doi: 10.3390/ijms26094028.
Aqueous biphasic catalysis has gained recognition as a sustainable and efficient method that combines the advantages of both homogeneous and heterogeneous catalytic systems. This approach enables the separation and recycling of catalysts, leading to reduced environmental impact and lower operational costs. A key component of this method is the use of transition metal catalysts, which are crucial for facilitating various reactions when paired with different types of ligands, primarily hydrophiles. This combination is essential for achieving high success rates in recyclable catalytic systems. The reaction conditions, including temperature, pressure, and pH, significantly influence catalytic performance. However, challenges such as limited substrate solubility and catalyst leaching persist, underscoring the need for further research into advanced ligand design, catalyst immobilization techniques, and scalable process integration. This review systematically examines recent experiments in the aqueous biphasic catalysis of olefins, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework. From an initial pool of 597 articles, 104 were found to be relevant and focused specifically on aqueous biphasic catalysis. The study investigates key reactions, the factors that influence these biphasic reactions, and the catalytic systems that facilitate them. By highlighting both progress and ongoing challenges, this work underscores the potential of aqueous biphasic catalysis to bridge the gap between green chemistry principles and industrial applications.
水相双相催化已成为一种可持续且高效的方法，它结合了均相和非均相催化体系的优点。这种方法能够实现催化剂的分离和循环利用，从而减少对环境的影响并降低运营成本。该方法的一个关键组成部分是使用过渡金属催化剂，当与主要为亲水性的不同类型配体配对时，过渡金属催化剂对于促进各种反应至关重要。这种组合对于在可循环催化体系中取得高成功率至关重要。反应条件，包括温度、压力和pH值，对催化性能有显著影响。然而，诸如底物溶解度有限和催化剂浸出等挑战仍然存在，这突出了对先进配体设计、催化剂固定化技术和可扩展工艺整合进行进一步研究的必要性。本综述按照系统评价和Meta分析的首选报告项目框架，系统地考察了烯烃水相双相催化的近期实验。从最初的597篇文章中，发现104篇相关文章并专门聚焦于水相双相催化。该研究调查了关键反应、影响这些双相反应的因素以及促进这些反应的催化体系。通过强调进展和持续存在的挑战，这项工作突出了水相双相催化在弥合绿色化学原理与工业应用之间差距方面的潜力。
