Zuddas A, Mulas S, Del Zompo M, Corsini G U
Cephalalgia. 1985 Jun;5(2):95-8. doi: 10.1046/j.1468-2982.1985.0502095.x.
Over the last ten years the efficacy of lithium salts in cluster headache has been well demonstrated. Our patient, who had been suffering from cluster headache for approximately 30 years, had been in haemodialysis treatment for the last ten years for chronic renal failure. Moreover, he was affected by heart failure and peptic ulcer. The patient was currently under therapy with Digitalis, Isorbide dinitrate, and ranitidine and was dialyzed three times a week for a total of five hours each time. Neither prophylactic headache therapy nor high doses of analgesic drugs had proved effective. Although this patient was in haemodialysis, lithium treatment was indicated. The administration of lithium carbonate 300 mg during dialysis days and 150 mg during non-dialysis days improved the attacks. Complete recovery from the attacks was obtained when the serum levels of lithium reached the therapeutic range. No side effects were noted.
在过去十年中，锂盐对丛集性头痛的疗效已得到充分证实。我们的患者患有丛集性头痛约30年，过去十年因慢性肾衰竭一直接受血液透析治疗。此外，他还患有心力衰竭和消化性溃疡。该患者目前正在接受洋地黄、硝酸异山梨酯和雷尼替丁治疗，每周透析三次，每次共五小时。预防性头痛治疗和高剂量镇痛药均未见效。尽管该患者正在接受血液透析，但仍需进行锂治疗。在透析日给予碳酸锂300毫克，非透析日给予150毫克，发作情况有所改善。当锂的血清水平达到治疗范围时，发作完全缓解。未观察到副作用。
