Bohr Nicole L, LaFond Cynthia M, Cazzell Mary, Gonzalez Monica, Laures Elyse, Perry-Eaddy Mallory A, Hanrahan Kirsten S, McCarthy Ann Marie
Department of Nursing Research and Evidence-Based Practice at UChicago Medicine, Chicago, Illinois, USA.
Nursing Research at Ascension Health, St. Louis, Missouri, USA.
Worldviews Evid Based Nurs. 2025 Apr;22(2):e70011. doi: 10.1111/wvn.70011.
Dissemination of results following clinical trials and community-based research provides value to participants and communities beyond the intent of the primary study. Organizations participating in multi-site research may see similar benefits if local results are shared; however, it is not standard practice. Evaluation of the impact of results sharing in multi-site research is needed.
To assess the benefits of organizational participation in a multi-site pediatric pain study when results were shared, identify how sites applied local results, and the outcomes of participation, including subsequent improvement efforts and scholarship.
Following data collection for a 12-hospital multi-site study, site research teams shared their experiences collecting the data and lessons learned. All sites received a packet with overall results, their local results, and an interpretation guide. 4 years later, the sites were surveyed about initiatives that were undertaken because of the primary study.
Following data collection, 10 of 12 sites described unanticipated benefits of participation, including identifying gaps and strengths of documentation, generation of new practice questions, and identification of new opportunities for improvement. Seven sites answered the follow-up survey 4 years later. Most sites (n = 6, 85.7%) used their data to inform multiple practice changes (M = 2.8, SD 0.75), including changes in pain documentation (n = 5, 83.3%), assessment (n = 4, 66.7%), policy (n = 4, 66.7%), and treatments (n = 4, 66.7%). Five sites reported an average of 2.4 (SD 1.14) additional activities stimulated by participation, but not directly due to data. Three sites used results for American Nurses Credentialing Center Magnet Recognition applications.
When multi-site investigators provide local data, organizations see long-term benefits, including new collaborations, quality improvement efforts, and research. Additional exploration of collaborative strategies between investigators and practice settings in multi-site research is needed for pediatric pain management and beyond.
临床试验和基于社区的研究结果的传播，为参与者和社区带来了超出主要研究意图的价值。参与多中心研究的组织如果分享本地结果，可能也会获得类似的益处；然而，这并非标准做法。需要评估多中心研究中结果分享的影响。
评估组织参与一项多中心儿科疼痛研究并分享结果时的益处，确定各中心如何应用本地结果以及参与的成果，包括后续的改进措施和学术成果。
在一项涉及12家医院的多中心研究完成数据收集后，各中心的研究团队分享了他们收集数据的经验和吸取的教训。所有中心都收到了一份包含总体结果、本地结果及解读指南的资料包。4年后，对各中心进行调查，了解因主要研究而开展的举措。
数据收集后，12个中心中有10个描述了参与研究带来的意外益处，包括发现记录方面的差距和优势、产生新的实践问题以及发现新的改进机会。4年后，7个中心回复了随访调查。大多数中心（n = 6，85.7%）利用其数据为多项实践变革提供依据（M = 2.8，标准差0.75），包括疼痛记录（n = 5，83.3%）、评估（n = 4，66.7%）、政策（n = 4，66.7%）和治疗（n = 4，66.7%）方面的变革。5个中心报告称，参与研究平均激发了2.4项（标准差1.14）额外活动，但并非直接源于数据。3个中心将结果用于美国护士认证中心的磁石医院认证申请。
当多中心研究人员提供本地数据时，组织会获得长期益处，包括新的合作、质量改进措施和研究。对于儿科疼痛管理及其他领域，需要进一步探索多中心研究中研究人员与实践机构之间的合作策略。
