Muel A S, Chaudun E, Courtois Y, Modak S P, Counis M F
Cell Differ. 1985 Jun;16(4):235-40. doi: 10.1016/0045-6039(85)90573-1.
The DNA repeat size is determined by micrococcal nuclease digestion kinetics and subsequent electrophoresis of the products among various chick embryonic tissues. The repeat size is found to be not significantly different from 193 to 197 bp, for brain and liver at 11 days and for lens epithelium and fiber at different embryonic stages. However, the pattern of micrococcal digestion seems to reveal an overall chromatin modification as a function of development in the lens fibers.
通过微球菌核酸酶消化动力学及随后对不同鸡胚组织中产物的电泳来确定DNA重复序列的大小。结果发现，对于11日龄的脑和肝以及不同胚胎阶段的晶状体上皮和纤维，重复序列大小在193至197碱基对之间无显著差异。然而，微球菌消化模式似乎揭示了晶状体纤维中作为发育函数的整体染色质修饰。
