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关于将使用迷幻剂的风险和危害降至最低

On Minimizing Risk and Harm in the Use of Psychedelics.

作者信息

Evans Jules, Aixalà Marc, Anderson Brian T, Brennan William, Bremler Rebecka, Breeksema Joost J, Burback Lisa, Calder Abigail E, Carhart-Harris Robin L, Cheung Katherine, Devenot Neşe, Gorman Ingmar, Greń Jakub, Hendricks Peter S, Holoyda Brian, Jacobs Edward, Krecké Joy, Kruger Daniel J, Luke David, Majić Tomislav, McGuire Amy L, Mehtani Nicky J, Mathai David S, Nash Kristin, Noorani Tehseen, Palitsky Roman, Robinson Oliver C, Simonsson Otto, Stahre Elin, van Elk Michiel, Yaden David B

机构信息

The Challenging Psychedelic Experiences Project London UK.

International Center for Ethnobotanical Education, Research and Services (ICEERS) Barcelona Spain.

出版信息

Psychiatr Res Clin Pract. 2025 Feb 11;7(1):4-8. doi: 10.1176/appi.prcp.20240128. eCollection 2025 Spring.

Abstract

OBJECTIVE

This article outlines recommendations from 30 psychedelic researchers on how to create a better psychedelic safety net.

METHODS

A survey of 30 psychedelic researchers asked them to identify key critical research gaps around psychedelic harm and safety.

RESULTS

The critical research gaps identified by the authors included defining the main types of psychedelic harm, the predictors of those harms, and the most effective way to treat those harms. They also call for better support for those experiencing post-psychedelic difficulties, including better online information, peer support groups, affordable therapy, and psychiatric consultation and medication. Finally, the authors call for better funding to create a psychedelic safety net, and suggest psychedelic philanthropists, investors and companies could commit 1% of their investment in psychedelics into supporting safety measures such as research and support services.

CONCLUSIONS

The authors identify several practical steps to create a better psychedelic safety net and call for more funding to psychedelic safety measures such as research and support services.

RELEVANCE TO CLINICAL PRACTICE

The authors outline important gaps in our knowledge around the safety and risk profile of psychedelic medicines and identify practical steps forward for researchers and clinical practitioners to make this promising field safer.

摘要

目的

本文概述了30位迷幻药研究人员关于如何建立更好的迷幻药安全保障的建议。

方法

对30位迷幻药研究人员进行了一项调查,询问他们确定围绕迷幻药危害和安全性的关键重要研究空白。

结果

作者确定的关键研究空白包括界定迷幻药危害的主要类型、这些危害的预测因素以及治疗这些危害的最有效方法。他们还呼吁为经历迷幻药后困难的人提供更好的支持,包括更好的在线信息、同伴支持小组、负担得起的治疗以及精神科咨询和药物治疗。最后,作者呼吁提供更多资金以建立迷幻药安全保障,并建议迷幻药慈善家、投资者和公司可以将其在迷幻药方面投资的1%用于支持研究和支持服务等安全措施。

结论

作者确定了建立更好的迷幻药安全保障的几个实际步骤,并呼吁为研究和支持服务等迷幻药安全措施提供更多资金。

与临床实践的相关性

作者概述了我们在迷幻药安全性和风险概况方面知识的重要空白,并为研究人员和临床从业者确定了使这个有前景的领域更安全的实际前进步骤。

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本文引用的文献

1
Proposed Consensus Statement on Defining Psychedelic Drugs.关于迷幻药物定义的拟议共识声明。
Psychedelic Med (New Rochelle). 2023 Mar 13;1(1):12-13. doi: 10.1089/psymed.2022.0008. eCollection 2023 Mar.
4
Psychedelic-related deaths in England, Wales and Northern Ireland (1997-2022).1997年至2022年英格兰、威尔士和北爱尔兰与迷幻剂相关的死亡情况。
Prog Neuropsychopharmacol Biol Psychiatry. 2025 Jan 10;136:111177. doi: 10.1016/j.pnpbp.2024.111177. Epub 2024 Oct 20.
5
Validation of the imperial psychedelic predictor scale.帝国迷幻预测量表的验证
Psychol Med. 2024 Sep 27;54(12):1-9. doi: 10.1017/S0033291724002204.
10
Essentials of Informed Consent to Psychedelic Medicine.知情同意在迷幻药医学中的要点。
JAMA Psychiatry. 2024 Jun 1;81(6):611-617. doi: 10.1001/jamapsychiatry.2024.0184.

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