Spence V A, McCollum P T, McGregor I W, Sherwin S J, Walker W F
Clin Phys Physiol Meas. 1985 May;6(2):139-45. doi: 10.1088/0143-0815/6/2/005.
Transcutaneous oxygen measurements (TCPO2) are being used increasingly for the assessment of tissue viability in the ischaemic limb. The major objective with such a technique is to determine the critical level of TCPO2 which defines the boundary between skin viability and non-viability. To be able to do this, an assumption is made that measurements from different centres using various TCPO2 sensors are comparable. This study shows that static and dynamic changes of TCPO2 (air to oxygen breathing) made with two commercially available instruments are not directly comparable. We suggest that the physical characteristics of present TCPO2 electrodes are not optimal for measurements on adult skin. TCPO2 measurements made in conditions of skin ischaemia should be interpreted with caution because the ratio of local oxygen demand to blood flow is such that the measurement may be underestimated by TCPO2 electrodes with a high oxygen consumption.
经皮氧测量（TCPO2）越来越多地用于评估缺血肢体的组织活力。使用这种技术的主要目的是确定界定皮肤存活与非存活界限的TCPO2临界水平。为了能够做到这一点，人们假定使用各种TCPO2传感器在不同中心进行的测量具有可比性。本研究表明，使用两种市售仪器进行的TCPO2（从空气呼吸到吸氧）的静态和动态变化并非直接可比。我们认为，目前的TCPO2电极的物理特性对于在成人皮肤上进行测量并非最佳。在皮肤缺血条件下进行的TCPO2测量应谨慎解释，因为局部氧需求与血流的比率使得具有高氧消耗的TCPO2电极可能会低估测量值。
