不同物种主动脉IV型胶原的比较分析。

Comparative analyses of aortic type IV collagen in various species.

作者信息

Leushner J R

出版信息

Comp Biochem Physiol B. 1985;81(2):367-72. doi: 10.1016/0305-0491(85)90327-x.

Abstract

Aortic type IV collagen from several species contained identical patterns of high-molecular-weight aggregates as determined by HPLC. Slab gel electrophoresis in one and two dimensions revealed a similar chain composition in these collagen samples. The basic structural components were similar in size to the long form of 7-S collagen. These studies suggest that a common supramolecular assembly of type IV chains exist within aortic basement membrane matrices.

摘要

通过高效液相色谱法测定，来自多个物种的主动脉IV型胶原蛋白含有相同模式的高分子量聚集体。一维和二维平板凝胶电泳显示这些胶原蛋白样品具有相似的链组成。基本结构成分的大小与7-S胶原蛋白的长形式相似。这些研究表明，主动脉基底膜基质中存在IV型链的常见超分子组装。