Perdrizet J A, Cummings J F, deLahunta A
Cornell Vet. 1985 Jul;75(3):401-10.
A case of presumptive organophosphate-induced delayed neurotoxicity in a bull is described. All signs were referable to a focal cervical or diffuse spinal cord lesion. These included recumbency with severe symmetrical paresis of all 4 limbs, the hind limb involvement being greater than the forelimbs. CSF analysis was normal. The bull was killed and necropsied. There were no gross CNS lesions. Histopathologic finds are characterized and their resemblance to lesions observed in delayed neurotoxicity caused by organophosphate compounds is discussed. The bull had been treated with organophosphate insecticide (famphur) 43 days prior to the onset of signs.
描述了一例公牛疑似有机磷诱导的迟发性神经毒性病例。所有症状均归因于局灶性颈部或弥漫性脊髓病变。这些症状包括四肢严重对称性轻瘫而卧地不起，后肢受累程度大于前肢。脑脊液分析正常。公牛被处死并进行尸检。中枢神经系统无明显病变。对组织病理学发现进行了特征描述，并讨论了其与有机磷化合物引起的迟发性神经毒性中观察到的病变的相似性。该公牛在出现症状前43天曾用有机磷杀虫剂（伐虫脒）进行治疗。
