Raviola G, Butler J M
Curr Eye Res. 1985 Apr;4(4):503-16. doi: 10.3109/02713688509025167.
We have either introduced into the vitreous space or perfused through the anterior chamber of macaque monkey eyes two anionic tracers, anionic ferritin (AF) and horseradish peroxidase (HRP) and a cationic probe, cationic ferritin (CF). We have observed that the anionic molecules, but not the cationic one, are transported to the blood stream by plasmalemmal vesicles of the endothelial cells in both the retinal and the iridial vasculature. We suggest that a variety of organic anions of different MW which are commonly present in the eye tissues may be returned to the blood by the same morphological mechanism.
我们已经将两种阴离子示踪剂，即阴离子铁蛋白（AF）和辣根过氧化物酶（HRP），以及一种阳离子探针，即阳离子铁蛋白（CF），注入猕猴眼的玻璃体腔或通过前房进行灌注。我们观察到，阴离子分子而非阳离子分子，通过视网膜和虹膜血管系统中内皮细胞的质膜小泡被转运至血流中。我们认为，眼组织中常见的各种不同分子量的有机阴离子可能通过相同的形态学机制返回血液。
