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辣根过氧化物酶在虹膜血管中的单向转运机制

Unidirectional transport mechanism of horseradish peroxidase in the vessels of the iris.

作者信息

Raviola G, Butler J M

出版信息

Invest Ophthalmol Vis Sci. 1984 Jul;25(7):827-36.

PMID:6735647
Abstract

When horseradish peroxidase (HRP) is introduced into the blood stream it is retained in the lumen of the iridial vessels. In this paper, we report that when the same tracer is perfused into the anterior chamber of macaque monkeys, it permeates the stroma of the iris and penetrates the lumen of iridial vessels by transcellular vesicular transport. This unidirectional movement of HRP out of the eye is not inhibited by ouabain or fluoroacetate.

摘要

当辣根过氧化物酶(HRP)被引入血流时,它会保留在虹膜血管腔内。在本文中,我们报告称,当将相同的示踪剂灌注到猕猴的前房时,它会渗透到虹膜基质中,并通过跨细胞囊泡运输穿透虹膜血管腔。HRP这种单向流出眼睛的运动不受哇巴因或氟乙酸盐的抑制。

相似文献

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Unidirectional transport mechanism of horseradish peroxidase in the vessels of the iris.辣根过氧化物酶在虹膜血管中的单向转运机制
Invest Ophthalmol Vis Sci. 1984 Jul;25(7):827-36.
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Unidirectional vesicular transport mechanism in retinal vessels.视网膜血管中的单向囊泡运输机制。
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Effects of paracentesis on the blood-aqueous barrier: an electron microscope study on Macaca mulatta using horseradish peroxidase as a tracer.
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Endothelial vesicles in the blood-brain barrier: are they related to permeability?血脑屏障中的内皮小泡:它们与通透性有关吗?
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Morphology and permeability properties of blood capillaries in extraocular muscles of macaque monkeys.
猕猴眼外肌中毛细血管的形态学和通透性特性
Graefes Arch Clin Exp Ophthalmol. 1985;223(1):9-15. doi: 10.1007/BF02150567.
4
Surface-associated vesicles in retinal arterioles and venules.视网膜小动脉和小静脉中的表面相关小泡。
Cell Tissue Res. 1986;245(2):431-7. doi: 10.1007/BF00213951.
5
Glucose transporters are abundant in cells with "occluding" junctions at the blood-eye barriers.葡萄糖转运蛋白在血眼屏障处具有“紧密连接”的细胞中大量存在。
Proc Natl Acad Sci U S A. 1990 Jun;87(11):4261-4. doi: 10.1073/pnas.87.11.4261.