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Retrospective analysis of pathological types and imaging features in pancreatic cancer: A comprehensive study.胰腺癌病理类型与影像特征的回顾性分析:一项综合研究。
World J Gastrointest Oncol. 2025 Jan 15;17(1):99153. doi: 10.4251/wjgo.v17.i1.99153.
2
Monitoring of circulating tumour DNA in advanced pancreatic ductal adenocarcinoma predicts clinical outcome and reveals disease progression earlier than radiological imaging.在晚期胰腺导管腺癌中监测循环肿瘤 DNA 可预测临床结局,并比影像学更早地揭示疾病进展。
Mol Oncol. 2023 Sep;17(9):1857-1870. doi: 10.1002/1878-0261.13472. Epub 2023 Jun 28.
3
Comprehensive ctDNA Measurements Improve Prediction of Clinical Outcomes and Enable Dynamic Tracking of Disease Progression in Advanced Pancreatic Cancer.全面的 ctDNA 测量可改善临床结局预测,并能动态跟踪晚期胰腺癌的疾病进展。
Clin Cancer Res. 2023 Apr 3;29(7):1267-1278. doi: 10.1158/1078-0432.CCR-22-3526.
4
Radiomics-based Machine-learning Models Can Detect Pancreatic Cancer on Prediagnostic Computed Tomography Scans at a Substantial Lead Time Before Clinical Diagnosis.基于放射组学的机器学习模型可以在临床诊断前相当长的时间内,通过预测性计算机断层扫描检测胰腺癌。
Gastroenterology. 2022 Nov;163(5):1435-1446.e3. doi: 10.1053/j.gastro.2022.06.066. Epub 2022 Jul 1.
5
18F-FDG PET/CT Imaging Biomarkers for Early and Late Evaluation of Response to First-Line Chemotherapy in Patients with Pancreatic Ductal Adenocarcinoma.18F-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描成像生物标志物用于胰腺导管腺癌患者一线化疗反应的早期和晚期评估
J Nucl Med. 2022 Feb;63(2):199-204. doi: 10.2967/jnumed.121.261952. Epub 2021 Jul 16.
6
The role of FDG PET/CT or PET/MRI in assessing response to neoadjuvant therapy for patients with borderline or resectable pancreatic cancer: a systematic literature review.氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描或正电子发射断层扫描/磁共振成像在评估边界性或可切除胰腺癌新辅助治疗反应中的作用:系统文献回顾。
Ann Nucl Med. 2021 Jul;35(7):767-776. doi: 10.1007/s12149-021-01629-0. Epub 2021 May 28.
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Evaluation of response using FDG-PET/CT and diffusion weighted MRI after radiochemotherapy of pancreatic cancer: a non-randomized, monocentric phase II clinical trial-PaCa-DD-041 (Eudra-CT 2009-011968-11).评价胰腺癌放化疗后使用 FDG-PET/CT 和弥散加权 MRI 的疗效:一项非随机、单中心 II 期临床试验-PaCa-DD-041(Eudra-CT 2009-011968-11)。
Strahlenther Onkol. 2021 Jan;197(1):19-26. doi: 10.1007/s00066-020-01654-4. Epub 2020 Jul 7.
9
Image-Based Molecular Phenotyping of Pancreatic Ductal Adenocarcinoma.基于图像的胰腺导管腺癌分子表型分析
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Preliminary study of tumor heterogeneity in imaging predicts two year survival in pancreatic cancer patients.影像学中肿瘤异质性的初步研究可预测胰腺癌患者的两年生存率。
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胰腺癌成像诊断框架的强化:批判性评估

Enhancing diagnostic frameworks in pancreatic cancer imaging: A critical appraisal.

作者信息

Dogru Galip Dogukan, Tugcu Ahmet Oguz, Dursun Cemal Ugur

机构信息

Department of Radiation Oncology, Gulhane Training and Research Hospital, Ankara 06010, Türkiye.

Department of Radiation Oncology, Kartal Dr. Lutfi Kirdar City Hospital, İstanbul 34865, Türkiye.

出版信息

World J Radiol. 2025 Mar 28;17(3):104818. doi: 10.4329/wjr.v17.i3.104818.

DOI:10.4329/wjr.v17.i3.104818
PMID:40176956
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11959621/
Abstract

This letter to the editor critically appraises the study by Luo . While the study provides valuable insights into imaging-pathology correlations in pancreatic cancer, we identify several opportunities for enhancing its clinical relevance. Notably, the exclusion of magnetic resonance cholangiopancreatography and positron emission tomography/computed tomography imaging limits the study's diagnostic scope, as these modalities offer superior capabilities in differentiating benign from malignant lesions and assessing metabolic tumor activity. Additionally, the retrospective, cross-sectional design restricts the potential for dynamic insights into disease progression. We also highlight the untapped potential of radiomics-based analyses, which could significantly improve diagnostic accuracy and prognostic assessments. We recommend integrating these advanced imaging modalities, adopting longitudinal study designs, and leveraging radiomics approaches in future research to enhance the diagnostic frameworks in pancreatic cancer imaging.

摘要

这封致编辑的信对罗的研究进行了批判性评估。虽然该研究为胰腺癌的影像-病理相关性提供了有价值的见解,但我们发现了几个增强其临床相关性的机会。值得注意的是,排除磁共振胰胆管造影和正电子发射断层扫描/计算机断层扫描成像限制了该研究的诊断范围,因为这些检查方式在区分良性与恶性病变以及评估代谢性肿瘤活性方面具有卓越的能力。此外,回顾性横断面设计限制了对疾病进展进行动态洞察的可能性。我们还强调了基于影像组学分析的未开发潜力,这可以显著提高诊断准确性和预后评估。我们建议在未来的研究中整合这些先进的成像方式,采用纵向研究设计,并利用影像组学方法来加强胰腺癌成像的诊断框架。