Li Lin, Peng Min, Zou Yifang, Li Yunxin, Qiao Peng
Department of Radiology, Yantaishan Hospital, Yantai, China.
Department of Radiology, Yantai Yuhuangding Hospital, Affiliated Hospital of Qingdao University, Yantai, China.
Front Med (Lausanne). 2025 Mar 19;12:1514931. doi: 10.3389/fmed.2025.1514931. eCollection 2025.
Computed tomography pulmonary angiography (CTPA) is an essential diagnostic tool for identifying pulmonary embolism (PE). The integration of AI has significantly advanced CTPA-based PE detection, enhancing diagnostic accuracy and efficiency. This review investigates the growing role of AI in the diagnosis of pulmonary embolism using CTPA imaging. The review examines the capabilities of AI algorithms, particularly deep learning models, in analyzing CTPA images for PE detection. It assesses their sensitivity and specificity compared to human radiologists. AI systems, using large datasets and complex neural networks, demonstrate remarkable proficiency in identifying subtle signs of PE, aiding clinicians in timely and accurate diagnosis. In addition, AI-powered CTPA analysis shows promise in risk stratification, prognosis prediction, and treatment optimization for PE patients. Automated image interpretation and quantitative analysis facilitate rapid triage of suspected cases, enabling prompt intervention and reducing diagnostic delays. Despite these advancements, several limitations remain, including algorithm bias, interpretability issues, and the necessity for rigorous validation, which hinder widespread adoption in clinical practice. Furthermore, integrating AI into existing healthcare systems requires careful consideration of regulatory, ethical, and legal implications. In conclusion, AI-driven CTPA-based PE detection presents unprecedented opportunities to enhance diagnostic precision and efficiency. However, addressing the associated limitations is critical for safe and effective implementation in routine clinical practice. Successful utilization of AI in revolutionizing PE care necessitates close collaboration among researchers, medical professionals, and regulatory organizations.
计算机断层扫描肺动脉造影(CTPA)是识别肺栓塞(PE)的重要诊断工具。人工智能的整合显著推进了基于CTPA的PE检测,提高了诊断准确性和效率。本综述研究了人工智能在使用CTPA成像诊断肺栓塞中日益增长的作用。该综述考察了人工智能算法,特别是深度学习模型,在分析CTPA图像以检测PE方面的能力。它评估了它们与人类放射科医生相比的敏感性和特异性。人工智能系统利用大型数据集和复杂的神经网络,在识别PE的细微迹象方面表现出卓越的能力,有助于临床医生进行及时准确的诊断。此外,人工智能驱动的CTPA分析在PE患者的风险分层、预后预测和治疗优化方面显示出前景。自动图像解读和定量分析有助于对疑似病例进行快速分类,实现及时干预并减少诊断延误。尽管有这些进展,但仍存在一些局限性,包括算法偏差、可解释性问题以及严格验证的必要性,这些都阻碍了其在临床实践中的广泛应用。此外,将人工智能整合到现有的医疗系统中需要仔细考虑监管、伦理和法律问题。总之,人工智能驱动的基于CTPA的PE检测为提高诊断精度和效率带来了前所未有的机会。然而,解决相关局限性对于在常规临床实践中安全有效地实施至关重要。要成功利用人工智能彻底改变PE护理,研究人员、医学专业人员和监管组织之间需要密切合作。