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使用鼻用类固醇冲洗液后的喉水肿和发声困难

Laryngeal Edema and Dysphonia After the Use of Nasal Steroid Rinses.

作者信息

Stewart Jasmine, Anderson Austin, Rutt Amy

机构信息

Department of Otolaryngology, New York Institute of Technology College of Osteopathic Medicine at Arkansas State, Jonesboro, USA.

Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic Florida, Jacksonville, USA.

出版信息

Cureus. 2025 Mar 3;17(3):e79954. doi: 10.7759/cureus.79954. eCollection 2025 Mar.

DOI:10.7759/cureus.79954
PMID:40177438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11963828/
Abstract

Chronic sinusitis and allergic rhinitis are common conditions characterized by the inflammation of the nasal and sinus mucosa. While traditionally associated with symptoms such as nasal congestion and facial pain, recent research has shown that these disorders can also have a broader impact on vocal function. These symptoms are usually managed with intranasal corticosteroid (INCS) rinses or systemic corticosteroids. We present a case of a 60-year-old man with a history of chronic, recurrent sinusitis in which the traditional treatment with intranasal corticosteroid rinses caused dysphonia, dysphagia, and laryngeal edema. After multiple clinic visits and the cessation of the rinses, the patient's symptoms resolved entirely.

摘要

慢性鼻窦炎和变应性鼻炎是常见病症,其特征为鼻腔和鼻窦黏膜的炎症。虽然传统上与鼻塞和面部疼痛等症状相关,但最近的研究表明,这些疾病也可能对嗓音功能产生更广泛的影响。这些症状通常通过鼻用皮质类固醇(INCS)冲洗或全身性皮质类固醇进行治疗。我们报告一例60岁男性患者,有慢性复发性鼻窦炎病史,使用鼻用皮质类固醇冲洗的传统治疗导致了发音困难、吞咽困难和喉水肿。经过多次门诊就诊并停止冲洗后,患者症状完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3153/11963828/f44a44a53559/cureus-0017-00000079954-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3153/11963828/c3b6bc439705/cureus-0017-00000079954-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3153/11963828/f44a44a53559/cureus-0017-00000079954-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3153/11963828/c3b6bc439705/cureus-0017-00000079954-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3153/11963828/f44a44a53559/cureus-0017-00000079954-i02.jpg

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本文引用的文献

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Review of evidence supporting the use of nasal corticosteroid irrigation for chronic rhinosinusitis.支持使用鼻用皮质类固醇冲洗治疗慢性鼻-鼻窦炎的证据综述。
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Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids.
糠酸莫米松局部用药与其他局部用皮质类固醇的安全性及疗效比较
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Mayo Clin Proc. 2012 Sep;87(9):901-4. doi: 10.1016/j.mayocp.2012.06.022.
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Functional limitations and workdays lost associated with chronic rhinosinusitis and allergic rhinitis.慢性鼻-鼻窦炎和变应性鼻炎相关的功能障碍和工作日损失。
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