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揭开基底动脉元凶:一位老年糖尿病患者的急性后循环卒中病例

Unmasking the Basilar Culprit: A Case of Acute Posterior Circulation Stroke in a Diabetic Septuagenarian.

作者信息

Akram Muhammad Rizwan, Veena Fnu, Sabah Afroze Fnu, Peachey Matthew, Elkin Rene

机构信息

Internal Medicine, BronxCare Health System, New York, USA.

Neurology, BronxCare Health System, New York, USA.

出版信息

Cureus. 2025 Mar 3;17(3):e79947. doi: 10.7759/cureus.79947. eCollection 2025 Mar.

DOI:10.7759/cureus.79947
PMID:40177451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11963212/
Abstract

A 76-year-old man with poorly controlled diabetes mellitus, with an HbA1c of 10.9% (4.7%-6.4%), presents with acute right facial numbness, transient right eye foggy vision, and near syncope. Neuroimaging revealed substantial basilar artery stenosis with acute infarction in the region of the right posterior cerebral artery, impacting the medial temporal, occipital, thalamus, and midbrain. Although basilar artery stenosis is uncommon, its combination with poorly managed diabetes and posterior circulation involvement makes therapy difficult. Partial neurological recovery was observed with dual antiplatelet treatment and intensive risk factor management. Basilar artery stenosis has a poor prognosis; however, early detection, medical therapy, and comorbidity control can improve patient outcomes and reduce recurrence risk. The example further emphasizes the necessity of preventative treatment in high-risk patients and the link between diabetes control and posterior circulation stroke risk.

摘要

一名76岁男性,糖尿病控制不佳,糖化血红蛋白(HbA1c)为10.9%(4.7%-6.4%),出现急性右侧面部麻木、右眼短暂视物模糊及近乎晕厥。神经影像学检查显示基底动脉严重狭窄,右侧大脑后动脉区域有急性梗死,累及颞叶内侧、枕叶、丘脑和中脑。尽管基底动脉狭窄并不常见,但它与糖尿病管理不善及后循环受累相结合使得治疗困难。通过双重抗血小板治疗和强化危险因素管理,观察到部分神经功能恢复。基底动脉狭窄预后不良;然而,早期检测、药物治疗和合并症控制可改善患者预后并降低复发风险。该病例进一步强调了高危患者预防性治疗的必要性以及糖尿病控制与后循环卒中风险之间的联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d57f/11963212/a5fde70dad89/cureus-0017-00000079947-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d57f/11963212/53f145bf3491/cureus-0017-00000079947-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d57f/11963212/a5fde70dad89/cureus-0017-00000079947-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d57f/11963212/53f145bf3491/cureus-0017-00000079947-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d57f/11963212/a5fde70dad89/cureus-0017-00000079947-i02.jpg

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本文引用的文献

1
Basilar Stenosis Reduces the Impact of Successful Recanalization on Outcome in Basilar Artery Occlusion.基底动脉狭窄降低了成功再通对基底动脉闭塞患者预后的影响。
Diagnostics (Basel). 2024 Oct 22;14(21):2348. doi: 10.3390/diagnostics14212348.
2
Focused update to guidelines for endovascular therapy for emergent large vessel occlusion: basilar artery occlusion patients.针对急性大血管闭塞:基底动脉闭塞患者的血管内治疗指南的重点更新。
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The use of dual antiplatelet therapy for ischemic cerebrovascular events.
双联抗血小板治疗用于缺血性脑血管事件。
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Treatment of posterior circulation stroke: Acute management and secondary prevention.治疗后循环卒中:急性处理与二级预防。
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Outcomes of Endovascular Therapy in Acute Basilar Artery Occlusion With Severe Symptoms.急性基底动脉闭塞伴严重症状的血管内治疗结局。
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Stroke. 2021 Jul;52(7):e468-e479. doi: 10.1161/STR.0000000000000377. Epub 2021 May 24.
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Isolated Focal Basilar Artery Stenosis with Acute Stroke Treated with Emergency Thrombectomy and Stenting.孤立性局灶性基底动脉狭窄伴急性卒中的急诊血栓切除术和支架置入治疗
Case Rep Neurol. 2020 Dec 14;12(Suppl 1):27-33. doi: 10.1159/000506973. eCollection 2020 Sep-Dec.
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Stroke mechanisms and outcomes of isolated symptomatic basilar artery stenosis.孤立性症状性基底动脉狭窄的卒中机制和结局。
Stroke Vasc Neurol. 2019 Jul 30;4(4):189-197. doi: 10.1136/svn-2019-000246. eCollection 2019 Dec.
9
Current endovascular strategies for posterior circulation large vessel occlusion stroke: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee.当前针对后循环大血管闭塞性脑卒中的血管内治疗策略:神经介入外科学会标准和指南委员会的报告。
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Poor glycemic control and posterior circulation ischemic stroke.血糖控制不佳与后循环缺血性卒中
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