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本文引用的文献

1
Primary Cutaneous Aspergillosis Due to in an Immunocompetent Patient with Diabetes Mellitus After Tattooing: A Case Report and Review of Literature.纹身术后糖尿病免疫功能正常患者发生原发性皮肤曲霉病：1例报告及文献复习
Infect Drug Resist. 2023 Feb 5;16:791-797. doi: 10.2147/IDR.S398858. eCollection 2023.
2
Mould Infections of Traumatic Wounds: A Brief Narrative Review.创伤伤口的霉菌感染：简要叙述性综述
Infect Dis Ther. 2020 Mar;9(1):1-15. doi: 10.1007/s40121-020-00284-8. Epub 2020 Feb 18.
3
Primary Cutaneous Aspergillosis in Immunocompetent Adults: Three Cases and a Review of the Literature.免疫功能正常成年人的原发性皮肤曲霉病：三例病例及文献综述
Cureus. 2020 Jan 8;12(1):e6600. doi: 10.7759/cureus.6600.
4
Issues with galactomannan testing.半乳甘露聚糖检测的问题。
Med Mycol. 2006 Sep 1;44(Supplement_1):S179-S183. doi: 10.1080/13693780600904918.
5
Primary cutaneous aspergillosis due to Aspergillus tamarii in an immunocompetent host.免疫功能正常宿主中由塔宾曲霉引起的原发性皮肤曲霉病。
BMJ Case Rep. 2013 Aug 22;2013:010128. doi: 10.1136/bcr-2013-010128.
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Post-operative aspergillosis.术后曲霉病
Clin Microbiol Infect. 2006 Nov;12(11):1060-76. doi: 10.1111/j.1469-0691.2006.01512.x.
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Cutaneous aspergillosis in patients with haematological malignancies.血液系统恶性肿瘤患者的皮肤曲霉病
Eur J Clin Microbiol Infect Dis. 2000 May;19(5):362-5. doi: 10.1007/s100960050495.
8
Cutaneous aspergillosis and acquired immunodeficiency syndrome.皮肤曲霉病与获得性免疫缺陷综合征
Arch Dermatol. 2000 Mar;136(3):365-9. doi: 10.1001/archderm.136.3.365.
9
Cutaneous aspergillosis.皮肤曲霉病
J Clin Microbiol. 1998 Nov;36(11):3115-21. doi: 10.1128/JCM.36.11.3115-3121.1998.
10
Fatal primary cutaneous aspergillosis in a bone marrow transplant recipient: nosocomial acquisition in a laminar-air flow room.一名骨髓移植受者发生致命性原发性皮肤曲霉病：在层流室发生医院内感染。
J Hosp Infect. 1997 Jul;36(3):235-9. doi: 10.1016/s0195-6701(97)90199-7.

创伤后长期中性粒细胞减少患者原发性皮肤侵袭性曲霉病简报

Brief Report on Primary Cutaneous Invasive Aspergillosis in a Patient With Prolonged Neutropenia Following a Traumatic Injury.

作者信息

Pérez Cortés Villalobos Armelle, Alahmadi Ghadeer, Rotstein Coleman

机构信息

Transplant Infectious Diseases, Multi-organ Transplant Program, University Health Network, Toronto, Ontario, Canada.

出版信息

Open Forum Infect Dis. 2025 Mar 7;12(4):ofaf140. doi: 10.1093/ofid/ofaf140. eCollection 2025 Apr.

DOI:10.1093/ofid/ofaf140
PMID:40177585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11962715/
Abstract

Primary cutaneous aspergillosis is a rare fungal infection that usually arises from direct inoculation of the skin. We present a case of a patient with acute leukemia who sustained a traumatic injury to his finger, which progressed to a severe necrotizing soft tissue fungal infection following the onset neutropenia. This case underscores the importance of early recognition and prompt initiation of antifungal treatment in patients who are immunocompromised, while highlighting the potential for rapid progression and severe outcomes.

摘要

原发性皮肤曲霉病是一种罕见的真菌感染，通常由皮肤直接接种引起。我们报告一例急性白血病患者，其手指遭受创伤性损伤，在出现中性粒细胞减少症后进展为严重的坏死性软组织真菌感染。该病例强调了对免疫功能低下患者早期识别并迅速启动抗真菌治疗的重要性，同时突出了病情快速进展和严重后果的可能性。