Beck D E, Harford F J, DiPalma J A
Dis Colon Rectum. 1985 Jul;28(7):491-5. doi: 10.1007/BF02554091.
Golytely, an oral gut lavage solution, was compared with a standard bowel cleansing preparation in patients undergoing elective colonic surgery. Sixty patients were randomly assigned to either a one-day preparation with Golytely and bisacodyl or a standard method using a three-day clear liquid diet, cathartics, and enemas. Colon cleansing was better with Golytely (100 percent optimal cleansing vs. 64 percent, P less than 0.05). Patients receiving Golytely had less weight loss and found this preparation more tolerable. Quantitative stool cultures before and after preparation and intraoperatively were not significantly different between the two preparations. In this surgical bowel preparation study, Golytely and Bisacodyl were found to be safe, rapid, and effective. The preparation was well tolerated by patients and has become our preferred method of colonic cleansing.
聚乙二醇电解质散（Golytely），一种口服肠道灌洗溶液，在接受择期结肠手术的患者中与标准肠道清洁准备方法进行了比较。60名患者被随机分配到使用聚乙二醇电解质散和比沙可啶进行一日准备组，或采用三日清流饮食、泻药和灌肠的标准方法组。聚乙二醇电解质散的结肠清洁效果更好（最佳清洁率为100%，而标准方法组为64%，P<0.05）。接受聚乙二醇电解质散的患者体重减轻更少，且觉得这种准备方法更易耐受。两种准备方法在准备前、准备后及术中的定量粪便培养结果无显著差异。在这项手术肠道准备研究中，发现聚乙二醇电解质散和比沙可啶安全、快速且有效。该准备方法患者耐受性良好，已成为我们首选的结肠清洁方法。
