聚乙二醇电解质灌洗液对肠道微生物群的影响。
Effect of polyethylene glycol-electrolyte lavage solution on intestinal microflora.
作者信息
Morotomi M, Guillem J G, Pocsidio J, LoGerfo P, Treat M, Forde K A, Weinstein I B, Watanabe I, Mutai M
机构信息
Department of Surgery, Columbia-Presbyterian Medical Center, New York, New York.
出版信息
Appl Environ Microbiol. 1989 Apr;55(4):1026-8. doi: 10.1128/aem.55.4.1026-1028.1989.
Abstract
The bacterial flora of colonic aspirates taken after oral administration of a polyethylene glycol-electrolyte lavage solution to patients undergoing colonoscopy was analyzed by standard bacteriological methods and DNA hybridization techniques. The data were compared with those for normal feces collected from the same patients the day before treatment. The results indicate that the bacterial composition of feces differs from individual to individual but is not altered by the oral intake of a polyethylene glycol-electrolyte lavage solution. This pilot study demonstrates that routine colonoscopy aspirates taken after standard colonoscopy preparation accurately reflect the microflora of feces and therefore may be used in large-scale epidemiological studies.
摘要
采用标准细菌学方法和DNA杂交技术，对接受结肠镜检查的患者口服聚乙二醇电解质灌洗液后采集的结肠吸出物中的细菌菌群进行了分析。将这些数据与治疗前一天从同一患者收集的正常粪便数据进行了比较。结果表明，粪便的细菌组成因人而异，但不会因口服聚乙二醇电解质灌洗液而改变。这项初步研究表明，标准结肠镜检查准备后采集的常规结肠镜吸出物能准确反映粪便的微生物群落，因此可用于大规模流行病学研究。
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