Wen Yong-Qiang, Wang Ya-Zhou, Zhao Chen-Xu, Zhao Bao-Yu, Wang Jian-Guo
College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
J Asian Nat Prod Res. 2025 Aug;27(8):1087-1111. doi: 10.1080/10286020.2025.2482054. Epub 2025 Apr 3.
Baicalin, a flavonoid derived from the dicotyledonous plant Georgi (SBG), is applied to treat various -disorders due to its various pharmacological effects such as anti-inflammatory, antiviral, antibacterial, liver-protecting, lipid-lowering, and neuroprotection. However, baicalin's limited solubility hampers absorption. This article reviews baicalin's pharmacological properties, including pharmacokinetics, cytotoxicity, drug interactions, and therapeutic potential, especially for cardiovascular diseases, obesity, and liver-lipid disorders, aiming to promote its development in medicine, dairy and livestock feed, nutritional health products and cosmetics for humans and other fields.
黄芩苷是一种从双子叶植物黄芩（Scutellaria baicalensis Georgi，SBG）中提取的黄酮类化合物，因其具有抗炎、抗病毒、抗菌、保肝、降脂和神经保护等多种药理作用，被用于治疗各种疾病。然而，黄芩苷有限的溶解度阻碍了其吸收。本文综述了黄芩苷的药理特性，包括药代动力学、细胞毒性、药物相互作用和治疗潜力，特别是对心血管疾病、肥胖症和肝脏脂质紊乱的治疗潜力，旨在促进其在医学、乳制品和家畜饲料、人类营养保健品和化妆品等领域的发展。
