Menéndez Fernández-Miranda Candela, Fernández-Suárez Jonathan, García Pérez Alicia, Boga José Antonio, Rodríguez-Pérez Mercedes, Rodríguez-Guardado Azucena
Servicio de Medicina Interna, Fundación Hospital de Avilés, Avilés, Spain.
Servicio de Microbiología, Hospital Universitario Central de Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.
Enferm Infecc Microbiol Clin (Engl Ed). 2025 Apr;43(4):219-226. doi: 10.1016/j.eimce.2025.03.010.
Dientamoeba fragilis is a protozoan of the gastrointestinal tract, very prevalent in our environment and responsible for diverse clinical symptoms mainly abdominal pain, diarrhoea and eosinophilia, although some infected patients are asymptomatic. Since the first description just a century ago, there are many unanswered questions: its different morphologies and the role of each of them, its actual prevalence, the mode of transmission, its pathogenicity, or the treatment of choice, continue to be source of controversy. Risk factors associated with infection by D. fragilis are: contact with children, residence in a rural area, and co-infection by Enterobius vermicularis. New molecular diagnostic techniques in the form of commercial multi-diagnostic panels are now considered first choice techniques. Paromomycin show higher cure rates, than metronidazole.
脆弱双核阿米巴是一种胃肠道原生动物,在我们的环境中非常普遍,可导致多种临床症状,主要是腹痛、腹泻和嗜酸性粒细胞增多,尽管一些感染者没有症状。自一个世纪前首次描述以来,仍有许多未解决的问题:它的不同形态及其各自的作用、实际流行率、传播方式、致病性或首选治疗方法,仍然存在争议。与脆弱双核阿米巴感染相关的危险因素有:与儿童接触、居住在农村地区以及蛲虫共感染。以商业多诊断试剂盒形式出现的新分子诊断技术现在被认为是首选技术。巴龙霉素的治愈率高于甲硝唑。