Klonoff David C, Berard Lori, Franco Denise Reis, Gentile Sandro, Gomez Olga Victoria, Hussein Zanariah, Jain Akshay B, Kalra Sanjay, Anhalt Henry, Mader Julia K, Miller Eden, O'Meara Miguel Augusto, Robins Michelle, Strollo Felice, Watada Hirotaka, Heinemann Lutz
Diabetes Research Institute, Mills-Peninsula Medical Center, San Mateo, CA.
Pink Pearls, Inc, Winnipeg, Manitoba, Canada.
Mayo Clin Proc. 2025 Apr;100(4):682-699. doi: 10.1016/j.mayocp.2025.01.004.
Injectable insulin therapy is a valuable therapeutic option for millions of people with diabetes worldwide. However, many people with diabetes undergoing insulin therapy experience suboptimal outcomes and/or have complications because of inadequate injection technique and training. Practical, current, evidence-based recommendations are mandatory for primary care practitioners and diabetes specialists alike to address unmet needs in insulin injection technique, education, and consequent outcomes. The most recent global insulin injection technique best practices were published in 2016 by the Forum for Injection Technique and Therapy Expert Recommendations (FITTER). While injection technique efforts in different regions have reflected some developments since 2016, a global effort was warranted to comprehensively capture new evidence and modern expert perspectives. In this article, we share the output of the "FITTER Forward" initiative, authored by 16 diabetes specialists from 13 countries who met virtually in 2023-2024. FITTER Forward provides an updated rationale for the importance of proper injection technique training and its impact on diabetes management. The FITTER Forward recommendations are organized for use in clinical practice and include 4 sections describing (1) the foundational science informing injection device design, experiences, and outcomes, (2) proper injection technique procedures for insulin pens and syringes from insulin storage to needle disposal, (3) lipodystrophy risk reduction, with a focus on lipohypertrophy, and (4) structured injection technique training programs for people with diabetes. Overall, FITTER Forward aims to better equip health care professionals to advance diabetes care by empowering people with diabetes and their caregivers to correctly and safely deliver insulin.
注射用胰岛素疗法对于全球数百万糖尿病患者而言是一种有价值的治疗选择。然而,许多接受胰岛素治疗的糖尿病患者由于注射技术和培训不足,治疗效果欠佳和/或出现并发症。对于初级保健医生和糖尿病专科医生来说,实用、最新且基于证据的建议对于解决胰岛素注射技术、教育及相关治疗效果方面未满足的需求至关重要。注射技术与治疗专家建议论坛(FITTER)于2016年发布了最新的全球胰岛素注射技术最佳实践。自2016年以来,不同地区在注射技术方面虽有一些进展,但仍需要全球共同努力以全面收集新证据和现代专家观点。在本文中,我们分享了“FITTER Forward”倡议的成果,该倡议由来自13个国家的16位糖尿病专家在2023 - 2024年通过线上会议完成。FITTER Forward为正确注射技术培训的重要性及其对糖尿病管理的影响提供了更新的理论依据。FITTER Forward建议按临床实践需求组织编写,包括4个部分,分别描述(1)为注射装置设计、经验和治疗效果提供依据的基础科学;(2)从胰岛素储存到针头处理,胰岛素笔和注射器的正确注射技术流程;(3)降低脂肪代谢障碍风险,重点关注脂肪增生;(4)针对糖尿病患者的结构化注射技术培训项目。总体而言,FITTER Forward旨在更好地武装医疗保健专业人员,通过使糖尿病患者及其护理人员能够正确、安全地注射胰岛素来推进糖尿病护理。