Cai Xing-Bo, Lu Ze-Hui, Peng Zhi, Xu Yong-Qing, Huang Jun-Shen, Luo Hao-Tian, Zhao Yu, Lou Zhong-Qi, Shen Zi-Qi, Chen Zhang-Cong, Yang Xiong-Gang, Wu Ying, Lu Sheng
Department of Orthopedic Surgery, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
The Key Laboratory of Digital Orthopaedics of Yunnan Province, Kunming, Yunnan, China.
Orthop Surg. 2025 May;17(5):1513-1524. doi: 10.1111/os.70034. Epub 2025 Apr 3.
Distal radius fractures account for 12%-17% of all fractures, with accurate classification being crucial for proper treatment planning. Studies have shown that in emergency settings, the misdiagnosis rate of hand/wrist fractures can reach up to 29%, particularly among non-specialist physicians due to a high workload and limited experience. While existing AI methods can detect fractures, they typically require large training datasets and are limited to fracture detection without type classification. Therefore, there is an urgent need for an efficient and accurate method that can both detect and classify different types of distal radius fractures. To develop and validate an intelligent classifier for distal radius fractures by combining a statistical shape model (SSM) with a neural network (NN) based on CT imaging data.
From August 2022 to May 2023, a total of 80 CT scans were collected, including 43 normal radial bones and 37 distal radius fractures (17 Colles', 12 Barton's, and 8 Smith's fractures). We established the distal radius SSM by combining mean values with PCA (Principal Component Analysis) features and proposed six morphological indicators across four groups. The intelligent classifier (SSM + NN) was trained using SSM features as input data and different fracture types as output data. Four-fold cross-validations were performed to verify the classifier's robustness. The SSMs for both normal and fractured distal radius were successfully established based on CT data. Analysis of variance revealed significant differences in all six morphological indicators among groups (p < 0.001). The intelligent classifier achieved optimal performance when using the first 15 PCA-extracted features, with a cumulative variance contribution rate exceeding 75%. The classifier demonstrated excellent discrimination capability with a mean area under the curve (AUC) of 0.95 in four-fold cross-validation, and achieved an overall classification accuracy of 97.5% in the test set. The optimal prediction threshold range was determined to be 0.2-0.4.
The SSMs for both normal and fractured distal radius were successfully established based on CT data. Analysis of variance revealed significant differences in all six morphological indicators among groups (p < 0.001). The intelligent classifier achieved optimal performance when using the first 15 PCA-extracted features, with a cumulative variance contribution rate exceeding 75%. The classifier demonstrated excellent discrimination capability with a mean AUC of 0.95 in four-fold cross-validation and achieved an overall classification accuracy of 97.5% in the test set. The optimal prediction threshold range was determined to be 0.2-0.4.
The CT-based SSM + NN intelligent classifier demonstrated excellent performance in identifying and classifying different types of distal radius fractures. This novel approach provides an efficient, accurate, and automated tool for clinical fracture diagnosis, which could potentially improve diagnostic efficiency and treatment planning in orthopedic practice.
桡骨远端骨折占所有骨折的12%-17%,准确分类对于正确的治疗方案规划至关重要。研究表明,在急诊环境中,手/腕部骨折的误诊率可达29%,尤其是在非专科医生中,因为工作量大且经验有限。虽然现有的人工智能方法可以检测骨折,但它们通常需要大量的训练数据集,并且仅限于骨折检测而不进行类型分类。因此,迫切需要一种高效且准确的方法,既能检测又能分类不同类型的桡骨远端骨折。通过基于CT成像数据将统计形状模型(SSM)与神经网络(NN)相结合,开发并验证一种用于桡骨远端骨折的智能分类器。
2022年8月至2023年5月,共收集了80例CT扫描,包括43例正常桡骨和37例桡骨远端骨折(17例Colles骨折、12例Barton骨折和8例Smith骨折)。我们通过将均值与主成分分析(PCA)特征相结合建立了桡骨远端SSM,并提出了四组中的六个形态学指标。使用SSM特征作为输入数据,不同骨折类型作为输出数据训练智能分类器(SSM+NN)。进行了四次交叉验证以验证分类器的稳健性。基于CT数据成功建立了正常和骨折桡骨远端的SSM。方差分析显示各组间所有六个形态学指标均存在显著差异(p<0.001)。当使用前15个PCA提取的特征时,智能分类器达到最佳性能,累积方差贡献率超过75%。该分类器在四次交叉验证中表现出优异的辨别能力,平均曲线下面积(AUC)为0.95,在测试集中总体分类准确率达到97.5%。确定最佳预测阈值范围为0.2-0.4。
基于CT数据成功建立了正常和骨折桡骨远端的SSM。方差分析显示各组间所有六个形态学指标均存在显著差异(p<0.001)。当使用前15个PCA提取的特征时,智能分类器达到最佳性能,累积方差贡献率超过75%。该分类器在四次交叉验证中表现出优异的辨别能力,平均AUC为0.95,在测试集中总体分类准确率达到97.5%。确定最佳预测阈值范围为0.2-0.4。
基于CT的SSM+NN智能分类器在识别和分类不同类型的桡骨远端骨折方面表现出优异的性能。这种新方法为临床骨折诊断提供了一种高效、准确和自动化的工具,有可能提高骨科实践中的诊断效率和治疗方案规划。