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腹腔镜胆囊切除术与机器人辅助胆囊切除术的比较分析:一项多中心回顾性研究。

Comparative Analysis of Laparoscopic and Robotic Cholecystectomy: A Multihospital Retrospective Study.

作者信息

Rhodes Marvin A, Otero Javier, Rochester Summer N, Blackhurst Dawn W, Schneider Andrew M

机构信息

Department of Surgery, University of South Carolina School of Medicine Greenville, Prisma Health-Upstate, Greenville, South Carolina.

出版信息

JSLS. 2025 Jan-Mar;29(1). doi: 10.4293/JSLS.2024.00068. Epub 2025 Apr 3.

Abstract

BACKGROUND AND OBJECTIVES

Laparoscopic cholecystectomy has remained the gold standard approach for gallbladder surgery for nearly 3 decades. However, adoption of robotics for treatment of gallbladder disease continues to grow. Despite this growth, clinical outcomes regarding laparoscopic versus robotic cholecystectomy remain unclear.

METHODS

We conducted a multihospital retrospective cohort study of patients who underwent cholecystectomy between August 1, 2021 and November 30, 2023. We compared demographic and clinical characteristics, surgical details, and postoperative outcomes between laparoscopic and robotic groups. The postoperative outcomes analyzed included conversion to open, bile leak, major duct injury, return to the operating room, surgical site infection, blood transfusion, readmission, and death. The overall complication rate included any of these outcomes. Statistical analysis included χ tests, -tests, Wilcoxon rank sum tests, and multivariable logistic regression.

RESULTS

A total of 4,316 patients were analyzed (3,736 laparoscopic, 580 robotic). In bivariate analyses, robotic surgery was associated with lower rates of conversion to open ( = .019), bleeding requiring transfusion ( = .017), and overall complications (2.9% vs 5.5%), respectively ( = .009). Robotic approach was associated with a 5 minute longer average surgery time ( = .002). Using multivariable logistic regression analysis to account for preoperative differences between the groups, robotic surgery was associated with a 62% decreased risk of any complication (odds ratio [OR] = 0.38, 95% confidence interval [CI] [0.20, 0.74]).

CONCLUSION

Robotic cholecystectomy demonstrates favorable clinical outcomes compared to laparoscopic cholecystectomy. These findings support the advantages of robotic assistance during cholecystectomy. To our knowledge, this represents one of the largest retrospective studies showing a clinical benefit from the robotic approach.

摘要

背景与目的

近30年来,腹腔镜胆囊切除术一直是胆囊手术的金标准术式。然而,采用机器人技术治疗胆囊疾病的情况仍在不断增加。尽管有这种增长,但腹腔镜与机器人辅助胆囊切除术的临床结局仍不明确。

方法

我们对2021年8月1日至2023年11月30日期间接受胆囊切除术的患者进行了一项多中心回顾性队列研究。我们比较了腹腔镜组和机器人辅助组的人口统计学和临床特征、手术细节及术后结局。分析的术后结局包括转为开腹手术、胆漏、主要胆管损伤、返回手术室、手术部位感染、输血、再次入院和死亡。总体并发症发生率包括上述任何一种结局。统计分析包括卡方检验、t检验、Wilcoxon秩和检验和多变量逻辑回归。

结果

共分析了4316例患者(3736例腹腔镜手术,580例机器人辅助手术)。在双变量分析中,机器人辅助手术分别与较低的转为开腹手术率(P = 0.019)、需要输血的出血率(P = 0.017)和总体并发症发生率(2.9%对5.5%,P = 0.009)相关。机器人辅助手术方式的平均手术时间长5分钟(P = 0.002)。使用多变量逻辑回归分析来考虑两组之间的术前差异,机器人辅助手术与任何并发症风险降低62%相关(优势比[OR]=0.38,95%置信区间[CI][0.20,0.74])。

结论

与腹腔镜胆囊切除术相比,机器人辅助胆囊切除术显示出良好的临床结局。这些发现支持了机器人辅助在胆囊切除术中的优势。据我们所知,这是显示机器人辅助手术方式具有临床益处的最大规模回顾性研究之一。

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本文引用的文献

1
Common Bile Duct Injury in Cholecystectomy.胆囊切除术中的胆总管损伤
JAMA Surg. 2024 May 1;159(5):591-592. doi: 10.1001/jamasurg.2023.8083.
4
New Technology and Bile Duct Injuries.新技术与胆管损伤
JAMA Surg. 2023 Dec 1;158(12):1311. doi: 10.1001/jamasurg.2023.4404.

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