Kul'chitskiĭ V A, Polenov S A, Cherniaevskaia G V
Fiziol Zh SSSR Im I M Sechenova. 1985 May;71(5):569-74.
In anesthetized cats, blockade of the intermediate chemosensitive area (area "S") of the ventral medulla by means of local cooling to 20-22 degrees C induced drop of arterial blood pressure by 22% as well as of the perfusion pressure in hind-limb skin-muscular and muscular preparations by 24% and 12%, resp. Analogous cooling of the caudal chemosensitive area (area "L") increased the BP by 6% as well as the perfusion pressure. Decentralizing of the hind-limbs prevented the perfusion pressure changes but did not affect the BP shifts. Raise of the temperature in the "S" area up to 41 degrees C increased both the BP and the perfusion pressure. Functional heterogeneity and role of the above chemosensitive areas in modulation of neurogenic vascular tone, are discussed.
在麻醉猫中，通过局部冷却至20 - 22摄氏度阻断延髓腹侧中间化学敏感区（“S”区），可使动脉血压下降22%，后肢皮肤 - 肌肉和肌肉制备物中的灌注压分别下降24%和12%。类似地，冷却尾部化学敏感区（“L”区）可使血压升高6%以及灌注压升高。后肢去神经支配可防止灌注压变化，但不影响血压变化。将“S”区温度升至41摄氏度可使血压和灌注压均升高。文中讨论了上述化学敏感区在神经源性血管张力调节中的功能异质性和作用。
