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[肺容积增加时全身及肺血流动力学的变化]

[Changes in systemic and pulmonary hemodynamics during an increase in lung volume].

作者信息

Danilov L N

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1985 May;71(5):593-8.

PMID:4018292
Abstract

15 anesthetized dogs were subjected to a gradual increase of the lungs volume by means of administration of the 50% gas mixture of oxygen and air. The exceeding of the lungs volume by 600 ml increased pressure in the caudal vein, reduced blood flow and systolic pressure in the heart ventricles. After administration of 800 ml of the gas, the systolic pressure started to raise in the right ventricle and achieved 36.8 mm Hg at the moment of intrathoracic pressure of 21.5 mm H2O and cessation of the minor circulation. Then the right ventricle augmented its mechanic activity inducing tachycardia, raise of the pressure up to 45.2 mm Hg and restoration of the lung circulation.

摘要

15只麻醉犬通过给予氧气和空气的50%混合气体使肺容积逐渐增加。肺容积超过600毫升会使尾静脉压力升高,减少心脏心室的血流量和收缩压。给予800毫升该气体后,右心室收缩压开始升高,在胸内压为21.5毫米水柱且微循环停止时达到36.8毫米汞柱。然后右心室增强其机械活动,引发心动过速,压力升至45.2毫米汞柱,并恢复肺循环。

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