• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

美国血管肉瘤的发病率、生存率及预后列线图趋势

Trends in the incidence, survival, and prognostic nomogram of angiosarcoma in the United States.

作者信息

Zeng Dong, Wang Zhiyi, Feng Yongdong, McKay Michael J, Masanam Monika K, Long Haixia, Cao Xi

机构信息

Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing, China.

Northern Cancer Service, Northwest Regional Hospital, Burnie, Tasmania, Australia.

出版信息

Medicine (Baltimore). 2025 Jan 3;104(1):e41152. doi: 10.1097/MD.0000000000041152.

DOI:10.1097/MD.0000000000041152
PMID:40184128
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11709153/
Abstract

This study aimed to investigate the epidemiological trends of angiosarcoma and to establish a tool to estimate its prognosis. Data from the Surveillance, Epidemiology, and End Results (SEER) database (1975-2016) were used to assess trends in the epidemiology of angiosarcoma, and a nomogram was established based on independent prognostic factors. The age-adjusted incidence of angiosarcoma gradually increased from 0.13/100,000 in 1975 to 0.33/100,000 in 2016 (annual percentage change [2.4]). The most significant increase was observed in patients aged ≥ 60 years. The same increasing trend was observed across all the stages and grades. The limited-duration prevalence increased from 0.0003% in 1992 to 0.0013% in 2016 (P < .05). In multivariable analyses, age, sex, marital status, grade, historical stage, surgery, site, and tumor size were independent prognostic factors for angiosarcoma. The concordance index of the nomogram was significantly higher than that of the American Joint Committee on Cancer (AJCC) 6th edition and the AJCC 7th edition (0.74 vs 0.61 vs 0.66, respectively). Calibration analysis showed optimal agreement between nomogram predictions and actual observations. The incidence and prevalence of angiosarcoma has increased over the past 40 years. We established a nomogram to predict the overall survival of patients with angiosarcoma.

摘要

本研究旨在调查血管肉瘤的流行病学趋势，并建立一种评估其预后的工具。利用监测、流行病学和最终结果（SEER）数据库（1975 - 2016年）的数据评估血管肉瘤的流行病学趋势，并基于独立预后因素建立了列线图。血管肉瘤的年龄调整发病率从1975年的0.13/10万逐渐增加到2016年的0.33/10万（年百分比变化[2.4]）。在≥60岁的患者中观察到最显著的增加。在所有分期和分级中均观察到相同的上升趋势。有限期患病率从1992年的0.0003%增加到2016年的0.0013%（P < 0.05）。在多变量分析中，年龄、性别、婚姻状况、分级、历史分期、手术、部位和肿瘤大小是血管肉瘤的独立预后因素。列线图的一致性指数显著高于美国癌症联合委员会（AJCC）第6版和第7版（分别为0.74对0.61对0.66）。校准分析显示列线图预测与实际观察之间具有最佳一致性。在过去40年中，血管肉瘤的发病率和患病率有所增加。我们建立了一个列线图来预测血管肉瘤患者的总生存期。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/86c0f8203ca9/medi-104-e41152-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/43f29fe190f9/medi-104-e41152-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/296fe8816c53/medi-104-e41152-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/c9b3eea02827/medi-104-e41152-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/ca2d821da4f3/medi-104-e41152-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/d7aa49a00870/medi-104-e41152-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/86c0f8203ca9/medi-104-e41152-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/43f29fe190f9/medi-104-e41152-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/296fe8816c53/medi-104-e41152-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/c9b3eea02827/medi-104-e41152-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/ca2d821da4f3/medi-104-e41152-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/d7aa49a00870/medi-104-e41152-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/858b/11709153/86c0f8203ca9/medi-104-e41152-g006.jpg

相似文献

1
Trends in the incidence, survival, and prognostic nomogram of angiosarcoma in the United States.美国血管肉瘤的发病率、生存率及预后列线图趋势
Medicine (Baltimore). 2025 Jan 3;104(1):e41152. doi: 10.1097/MD.0000000000041152.
2
A Clinical Model of Bone Angiosarcoma Patients: A Population-based Analysis of Epidemiology, Prognosis, and Treatment.骨血管肉瘤患者的临床模型：基于人群的流行病学、预后和治疗分析。
Orthop Surg. 2020 Dec;12(6):1652-1662. doi: 10.1111/os.12803. Epub 2020 Sep 10.
3
Epidemiology, tumor characteristics and survival in patients with angiosarcoma in the United States: a population-based study of 4537 cases.美国血管肉瘤患者的流行病学、肿瘤特征和生存情况：基于人群的 4537 例病例研究。
Jpn J Clin Oncol. 2019 Dec 27;49(12):1092-1099. doi: 10.1093/jjco/hyz113.
4
A nomogram to predict postoperative overall and cancer specific survival in patients with primary parotid squamous cell carcinoma: a population based study.预测原发性腮腺鳞状细胞癌患者术后总体生存率和癌症特异性生存率的列线图：一项基于人群的研究。
Sci Rep. 2025 Feb 25;15(1):6774. doi: 10.1038/s41598-025-90480-8.
5
New nomograms to predict overall and cancer-specific survival of angiosarcoma.新的列线图预测血管肉瘤的总生存和癌特异性生存。
Cancer Med. 2022 Jan;11(1):74-85. doi: 10.1002/cam4.4425. Epub 2021 Nov 16.
6
Epidemiologic Trends of and Factors Associated With Overall Survival for Patients With Gastroenteropancreatic Neuroendocrine Tumors in the United States.美国胃肠胰神经内分泌肿瘤患者总体生存的流行病学趋势及相关因素。
JAMA Netw Open. 2021 Sep 1;4(9):e2124750. doi: 10.1001/jamanetworkopen.2021.24750.
7
A prognostic nomogram for the cancer-specific survival of patients with upper-tract urothelial carcinoma based on the Surveillance, Epidemiology, and End Results Database.基于监测、流行病学和最终结果数据库的上尿路上皮癌患者癌症特异性生存的预后列线图。
BMC Cancer. 2020 Jun 8;20(1):534. doi: 10.1186/s12885-020-07019-5.
8
Epidemiological features of primary breast lymphoma patients and development of a nomogram to predict survival.原发性乳腺淋巴瘤患者的流行病学特征和生存预测列线图的建立。
Breast. 2021 Jun;57:49-61. doi: 10.1016/j.breast.2021.03.006. Epub 2021 Mar 17.
9
A nomogram incorporating treatment data for predicting overall survival in gastroenteropancreatic neuroendocrine tumors: a population-based cohort study.纳入治疗数据的列线图预测胃肠胰神经内分泌肿瘤患者的总生存：一项基于人群的队列研究。
Int J Surg. 2024 Apr 1;110(4):2178-2186. doi: 10.1097/JS9.0000000000001080.
10
Prognostic nomogram for predicting the overall survival rate of patients with uterine clear-cell carcinoma: Based on SEER database.基于 SEER 数据库的预测子宫透明细胞癌患者总生存率的预后列线图
Int J Gynaecol Obstet. 2024 Aug;166(2):707-717. doi: 10.1002/ijgo.15456. Epub 2024 Mar 5.

本文引用的文献

1
Cutaneous Angiosarcoma.皮肤血管肉瘤
JAMA Otolaryngol Head Neck Surg. 2024 Aug 1;150(8):746-748. doi: 10.1001/jamaoto.2024.1715.
2
Angiosarcoma of the breast: A review.乳腺血管肉瘤：综述
Heliyon. 2024 Jan 19;10(3):e24413. doi: 10.1016/j.heliyon.2024.e24413. eCollection 2024 Feb 15.
3
Establishment and assessment of a nomogram for predicting prognosis in bone-metastatic prostate cancer.建立和评估预测骨转移前列腺癌预后的列线图。
Medicine (Baltimore). 2023 Nov 3;102(44):e35693. doi: 10.1097/MD.0000000000035693.
4
Cutaneous Angiosarcoma of the Head and Neck-A Retrospective Analysis of 47 Patients.头颈部皮肤血管肉瘤——47例患者的回顾性分析
Cancers (Basel). 2022 Aug 8;14(15):3841. doi: 10.3390/cancers14153841.
5
Breast angiosarcoma after primary breast cancer surgery: A systematic review.原发性乳腺癌手术后的乳腺血管肉瘤：一项系统综述。
J Plast Reconstr Aesthet Surg. 2022 Sep;75(9):2882-2889. doi: 10.1016/j.bjps.2022.06.046. Epub 2022 Jun 21.
6
Cutaneous Angiosarcomas: Molecular Pathogenesis Guides Novel Therapeutic Approaches.皮肤血管肉瘤：分子发病机制指导新型治疗方法
J Dtsch Dermatol Ges. 2022 Apr;20(4):429-443. doi: 10.1111/ddg.14694. Epub 2022 Feb 26.
7
Management of Cutaneous Angiosarcoma: an Update Review.皮肤血管肉瘤的管理：最新综述
Curr Treat Options Oncol. 2022 Feb;23(2):137-154. doi: 10.1007/s11864-021-00933-1. Epub 2022 Feb 19.
8
Characteristics and outcomes of primary pleural angiosarcoma: A retrospective study of 43 published cases.原发性胸膜血管肉瘤的特征和结局：43 例病例的回顾性研究。
Medicine (Baltimore). 2022 Feb 11;101(6):e28785. doi: 10.1097/MD.0000000000028785.
9
Association between occupational exposures and sarcoma incidence and mortality: systematic review and meta-analysis.职业暴露与肉瘤发病率和死亡率的关系：系统评价和荟萃分析。
Syst Rev. 2021 Aug 13;10(1):231. doi: 10.1186/s13643-021-01769-4.
10
Spleen angiosarcoma: a world review.脾脏血管肉瘤：世界范围内的回顾。
Expert Rev Gastroenterol Hepatol. 2021 Oct;15(10):1115-1141. doi: 10.1080/17474124.2021.1945920. Epub 2021 Jul 22.