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乳腺血管肉瘤:综述

Angiosarcoma of the breast: A review.

作者信息

An Ran, Men Xiao-Juan, Ni Xi-Hao, Wang Wei-Tao, Wang Chang-Liang

机构信息

School of Clinical Medicine, Shandong Second Medical University, Weifang 261041, Shandong Province, China.

Department of Thyroid and Breast Surgery, Weifang People's Hospital, Weifang 261041, Shandong Province, China.

出版信息

Heliyon. 2024 Jan 19;10(3):e24413. doi: 10.1016/j.heliyon.2024.e24413. eCollection 2024 Feb 15.

Abstract

Breast angiosarcoma is a rare and highly aggressive malignancy with a poor prognosis. It can occur spontaneously or be associated with factors such as radiation therapy or chronic lymphedema. The etiology and pathogenesis of this disease are still unclear, the clinical symptoms and imaging findings lack specificity, and the pathological morphology is diverse, which is easy to be confused with other diseases. There is no clear guideline for surgical treatment. Although the optimal surgical approach remains unclear, the ultimate goal is surgical excision with optimal margins, which remains the primary method of treatment. In clinical practice, the choice of the surgical approach should be made by considering the tumor size, pathological type, and patient preferences. In clinical practice, the selection of surgical methods should be carried out with comprehensive consideration of tumor size, pathological types and patients' wishes. There is no clear consensus on whether radiotherapy and chemotherapy should be carried out after surgery, and its optimal program and efficacy are uncertain. This article reviews the etiology, clinical manifestations, pathological features, imaging findings, treatment, prognosis and other aspects of breast angiosarcoma, so as to strengthen clinicians' overall understanding of this disease and avoid missed diagnosis and misdiagnosis.

摘要

乳腺血管肉瘤是一种罕见且侵袭性很强的恶性肿瘤,预后较差。它可自发发生,或与放疗、慢性淋巴水肿等因素有关。该病的病因和发病机制尚不清楚,临床症状和影像学表现缺乏特异性,病理形态多样,容易与其他疾病混淆。目前尚无明确的手术治疗指南。虽然最佳手术方式仍不明确,但最终目标是进行切缘阴性的手术切除,这仍是主要的治疗方法。在临床实践中,手术方式的选择应综合考虑肿瘤大小、病理类型和患者意愿。对于术后是否应进行放疗和化疗,目前尚无明确共识,其最佳方案和疗效也不确定。本文对乳腺血管肉瘤的病因、临床表现、病理特征、影像学表现、治疗、预后等方面进行综述,以增强临床医生对该病的全面认识,避免漏诊和误诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61d2/10839862/3ccf7d3fa07e/gr1.jpg

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