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卵巢分泌孕酮的支持细胞瘤

Progesterone secreting Sertoli cell tumor of the ovary.

作者信息

Tracy S L, Askin F B, Reddick R L, Jackson B, Kurman R J

出版信息

Gynecol Oncol. 1985 Sep;22(1):85-96. doi: 10.1016/0090-8258(85)90011-3.

DOI:10.1016/0090-8258(85)90011-3
PMID:4018664
Abstract

A 33-year-old woman presenting with secondary amenorrhea and galactorrhea was found to have a Sertoli cell tumor of the ovary. The neoplasm also had a sex cord tumor with annular tubules (SCTAT) component. Further investigations revealed that in many respects the patient was endocrinologically pregnant. She had markedly elevated serum estrogen and progesterone levels and the endometrium demonstrated pronounced decidualization, but there was no evidence of actual pregnancy. Estrogen and progesterone were demonstrated by immunohistochemistry to be present in both the Sertoli cell and SCTAT portions of the tumor.

摘要

一名33岁出现继发性闭经和溢乳的女性被发现患有卵巢支持细胞瘤。该肿瘤还具有环状小管性索肿瘤(SCTAT)成分。进一步检查发现,在许多方面该患者处于内分泌学意义上的妊娠状态。她的血清雌激素和孕激素水平显著升高,子宫内膜呈现明显的蜕膜化,但没有实际妊娠的证据。通过免疫组织化学证实雌激素和孕激素存在于肿瘤的支持细胞和SCTAT部分。

相似文献

1
Progesterone secreting Sertoli cell tumor of the ovary.卵巢分泌孕酮的支持细胞瘤
Gynecol Oncol. 1985 Sep;22(1):85-96. doi: 10.1016/0090-8258(85)90011-3.
2
Does ovarian sex cord tumour with annular tubules produce progesterone?伴环状小管的卵巢性索肿瘤会产生孕酮吗?
J Clin Pathol. 1986 Jan;39(1):29-35. doi: 10.1136/jcp.39.1.29.
3
Ovarian sex cord tumor with annular tubules--a case report and review of the literature in Japanese.伴有环状小管的卵巢性索肿瘤——1例报告及日文文献复习
Hiroshima J Med Sci. 1992 Jun;41(2):37-42.
4
Estrogen-producing Sertoli cell tumor of the ovary--a case report.卵巢产生雌激素的支持细胞瘤——病例报告
Gynecol Oncol. 1984 Nov;19(3):348-54. doi: 10.1016/0090-8258(84)90202-6.
5
AFP-producing Sertoli-Leydig cell tumor of the ovary.卵巢产生甲胎蛋白的支持-间质细胞瘤。
Arch Gynecol. 1985;236(3):187-96. doi: 10.1007/BF02133963.
6
An immunohistological study of steroid localization in Sertoli-Leydig tumors of the ovary and testis.
Cancer. 1978 Oct;42(4):1772-83. doi: 10.1002/1097-0142(197810)42:4<1772::aid-cncr2820420416>3.0.co;2-w.
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Sertoli-Leydig cell tumor of the ovary producing alpha-fetoprotein.卵巢支持-间质细胞瘤伴甲胎蛋白分泌
Int J Gynecol Pathol. 1984;3(2):213-9. doi: 10.1097/00004347-198402000-00009.
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Sertoliform endometrioid carcinomas of the ovary: a clinicopathologic and immunohistochemical study of 13 cases.卵巢塞尔托利样子宫内膜样癌:13例临床病理及免疫组化研究
Mod Pathol. 1999 Oct;12(10):933-40.
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Recurrent alpha-fetoprotein secreting Sertoli-Leydig cell tumor of ovary with an unusual presentation.复发性分泌甲胎蛋白的卵巢支持-间质细胞瘤伴不寻常表现。
Indian J Cancer. 2009 Jan-Mar;46(1):64-6. doi: 10.4103/0019-509x.48599.
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A pure Sertoli cell tumor of the ovary in a 10-year-old female.一名10岁女性的卵巢纯支持细胞瘤。
J Pediatr Adolesc Gynecol. 2007 Aug;20(4):257-9. doi: 10.1016/j.jpag.2007.04.009.

引用本文的文献

1
Ovarian tumors with functioning manifestations.具有功能性表现的卵巢肿瘤
Endocr Pathol. 1994 Sep;5(3):137-148. doi: 10.1007/BF02921469.
2
Hormone-producing tumors of the ovary.卵巢的激素分泌性肿瘤。
Endocr Pathol. 1990 Sep;1(3):132-171. doi: 10.1007/BF02915390.
3
The utility of adrenal and ovarian venous sampling in a progesterone-producing adrenal tumor and review of the literature.促肾上腺皮质激素和卵巢静脉取样在产生孕激素的肾上腺肿瘤中的应用及文献复习。
Endocrine. 2019 Nov;66(2):319-325. doi: 10.1007/s12020-019-02007-7. Epub 2019 Aug 27.
4
Endocrine pathology of the ovary : in tribute to Robert E Scully, MD.卵巢内分泌病理学:致敬医学博士罗伯特·E·斯库利
Endocr Pathol. 2014 Mar;25(1):102-19. doi: 10.1007/s12022-013-9285-4.
5
In vitro malignant transformation of in vivo ENU-induced rat ovarian Sertoli cell tumor (adenoma).体内ENU诱导的大鼠卵巢支持细胞瘤(腺瘤)的体外恶性转化
J Cancer Res Clin Oncol. 1988;114(2):142-8. doi: 10.1007/BF00417828.