Golden C J, Scott M, Strider M A, Chung C C, Ruedrich S, Graber B
Hillside J Clin Psychiatry. 1985;7(1):3-15.
The paper examined the relationship between the scales of the Luria Nebraska Neuropsychological Battery and measures of cerebral blood flow in a sample of 51 chronic schizophrenic patients without a history of brain damage. Of 88 correlations between the two sets of data, 22 were significant at the .05 level. The measurement of left anterior gray flow were particularly predictive of LNNB scores, although all correlations were at a moderate level, ranging from -.24 to -.38. The data are consistent with the hypothesis that neuropsychological testing performance in schizophrenics is related to brain function rather than merely reflecting deficits due to anxiety or other psychiatric features which have been hypothesized to invalidate neuropsychological assessment in this population. The data are also consistent with the notion that schizophrenia is more likely associated with left-anterior functioning, and that gray-matter measures in rCBF are effective predictors of neuropsychological performance.
该论文研究了51名无脑损伤病史的慢性精神分裂症患者样本中，鲁利亚-内布拉斯加神经心理成套测验的量表与脑血流量测量值之间的关系。在两组数据的88个相关性中，有22个在0.05水平上具有显著性。左前灰质血流量的测量对鲁利亚-内布拉斯加神经心理成套测验分数具有特别的预测性，尽管所有相关性都处于中等水平，范围从-0.24到-0.38。这些数据与以下假设一致：精神分裂症患者的神经心理测试表现与脑功能有关，而不仅仅反映由于焦虑或其他精神特征导致的缺陷，这些特征被认为会使该人群的神经心理评估无效。这些数据也与以下观点一致：精神分裂症更可能与左前功能相关，并且rCBF中的灰质测量是神经心理表现的有效预测指标。
