Murugesan Perumal, Kogularasu Sakthivel, Chen Yung-Lung, Lee Yen-Yi, Chang-Chien Guo-Ping, Govindasamy Mani
International PhD Program in Innovative Technology of Biomedical Engineering and Medical Devices, Ming Chi University of Technology, New Taipei City 243303, Taiwan; Research Center for Intelligence Medical Devices, Ming Chi University of Technology, New Taipei City 243303, Taiwan.
Super Micro Mass Research and Technology Center, Cheng Shiu University, Kaohsiung 833301, Taiwan; Center for Environmental Toxin and Emerging-Contaminant Research, Cheng Shiu University, Kaohsiung 833301, Taiwan.
Food Chem. 2025 Aug 1;482:144168. doi: 10.1016/j.foodchem.2025.144168. Epub 2025 Mar 31.
Detecting harmful feed additives in animal-derived foods is essential due to potential health and environmental risks. Given its toxicity, Roxarsone, a common organoarsenic compound, requires sensitive detection methods. This study introduces an electrochemical sensor using a glassy carbon electrode modified with 2D MXene (TiCTₓ) layered with silver telluride (AgTe). Characterization through XRD, FT-IR, and XPS confirmed the sensor's composition. Electrochemical assessments using cyclic voltammetry and differential pulse voltammetry showed notable electron transfer and catalytic efficiency improvements. The sensor exhibited a broad detection range for roxarsone (0.03-2310 μM) with an ultra-low detection limit (0.32 nM) and demonstrated excellent reproducibility (RSD < 3 %), stability, and selectivity. Real sample analysis in meat products confirmed its practical application, achieving high recovery rates. This work offers a robust approach for roxarsone detection, employing MXene and AgTe's synergistic properties to enhance food safety and environmental monitoring.
由于存在潜在的健康和环境风险，检测动物源性食品中的有害饲料添加剂至关重要。鉴于其毒性，常见的有机砷化合物洛克沙胂需要灵敏的检测方法。本研究介绍了一种电化学传感器，该传感器使用涂覆有碲化银（AgTe）的二维MXene（TiCTₓ）修饰的玻碳电极。通过X射线衍射（XRD）、傅里叶变换红外光谱（FT-IR）和X射线光电子能谱（XPS）进行的表征证实了该传感器的组成。使用循环伏安法和差分脉冲伏安法进行的电化学评估表明，电子转移和催化效率有显著提高。该传感器对洛克沙胂具有较宽的检测范围（0.03 - 2310 μM），检测限极低（0.32 nM），并表现出出色的重现性（相对标准偏差<3%）、稳定性和选择性。肉制品的实际样品分析证实了其实际应用效果，回收率很高。这项工作提供了一种用于检测洛克沙胂的可靠方法，利用MXene和AgTe的协同特性来加强食品安全和环境监测。
