Zhao Yuan, Jiang Yueying, Xu Qunyan, Chen Dandan, Tang Panpan, Wang Xueqing, Guo Yunyu, Liu Chang, Feng Xiuqin, Tang Leiwen
Department of Nursing, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
Clinical and Health Sciences, University of South Australia, Adelaide, South Australia.
Sci Rep. 2025 Apr 5;15(1):11728. doi: 10.1038/s41598-025-94485-1.
We aim to explore the contributing factors to intrinsic capacity (IC) in middle-aged and older patients after percutaneous coronary intervention (PCI). Intrinsic capacity comprises six core domains: cognition, locomotion, vitality, psychology, vision, and hearing. Each domain was assessed in detail using different scales, based on which the composite IC score was calculated. The study employed latent class analysis (LCA) to identify the various IC subtypes. Logistic regression analyses were used to determine the effect variables of IC subtypes. 318 middle-aged and older post-PCI patients filled out the assessments. Three distinct IC subtypes were found: 47.8% poor audition-vision group (class 1), 38% high cognition-psychology group (class 2), and 14.2% low locomotion-vitality group (class 3). The IC subtype classification may be impacted by factors such as cTnI, NT proBNP, cardiac function, exercise frequency, and comorbidities. Examining IC subtypes may be helpful for focused intervention, and further empirical research is still needed to determine their drivers.
我们旨在探究经皮冠状动脉介入治疗（PCI）后中老年患者内在能力（IC）的影响因素。内在能力包括六个核心领域：认知、运动、活力、心理、视觉和听觉。使用不同量表对每个领域进行详细评估，并据此计算综合IC评分。该研究采用潜在类别分析（LCA）来识别不同的IC亚型。采用逻辑回归分析来确定IC亚型的影响变量。318例PCI术后中老年患者完成了评估。发现了三种不同的IC亚型：47.8%的听觉-视觉较差组（1类）、38%的认知-心理较高组（2类）和14.2%的运动-活力较低组（3类）。IC亚型分类可能受到肌钙蛋白I（cTnI）、N末端脑钠肽前体（NT proBNP）、心功能、运动频率和合并症等因素的影响。检查IC亚型可能有助于进行有针对性的干预，仍需要进一步的实证研究来确定其驱动因素。
