Zegrea Adrian, Ojala Emilia, Kirss Jaan, Suvitie Pia, Varpe Pirita, Mäkelä-Kaikkonen Johanna, Rautio Tero, Seikkula Jaana, Ukkonen Mika, Lavonius Maija, Pinta Tarja
Seinäjoki Central Hospital, Seinäjoki, Finland.
Turku University Hospital and University of Turku, Turku, Finland.
BMC Womens Health. 2025 Apr 7;25(1):162. doi: 10.1186/s12905-025-03699-y.
Sacral neuromodulation (SNM) is an established therapy in urology and gastroenterological surgery for treatment of overactive bladder symptoms, urge urinary incontinence or fecal incontinence. SNM has also been used with good results in patients with chronic pelvic pain (CPP). Our aim was to analyze long-term results of SNM in Finnish patients with endometriosis related CPP.
This is a register-based retrospective study including all the endometriosis patients treated with SNM for CPP in Finland between 2004 and 2017. There were four centers where these procedures were performed, two University Hospitals and two Central Hospitals. Long-term results were assessed by phone interview in spring 2021.
A total of 16 women with endometriosis, with a median age of 39 (25-50) years, underwent SNM treatment for chronic pelvic pain (CPP), with the median follow-up time of 73 (48-85) months. The Implantable Pulse Generator (IPG) was implanted to 14 patients (88%). By the end of the follow-up period, 10 patients (62,5% of all patients and 71% of those who received IPG) had a functional SNM. Pain was assessed by numeral rating scale (NRS) and decreased from a median of 7.4 (3.6-10) to 2.3 (0-6.5).
SNM could be a good option in the treatment of endometriosis related chronic pelvic pain when standard therapy is not enough.
骶神经调节（SNM）是泌尿外科和胃肠外科用于治疗膀胱过度活动症症状、急迫性尿失禁或大便失禁的一种成熟疗法。SNM在慢性盆腔疼痛（CPP）患者中也有良好疗效。我们的目的是分析SNM治疗芬兰子宫内膜异位症相关性CPP患者的长期疗效。
这是一项基于登记的回顾性研究，纳入了2004年至2017年期间在芬兰接受SNM治疗CPP的所有子宫内膜异位症患者。有四个中心进行了这些手术，两个大学医院和两个中心医院。2021年春季通过电话访谈评估长期疗效。
共有16名子宫内膜异位症女性，中位年龄39（25 - 50）岁，接受了SNM治疗慢性盆腔疼痛（CPP），中位随访时间73（48 - 85）个月。14名患者（88%）植入了植入式脉冲发生器（IPG）。随访期末，10名患者（占所有患者的62.5%，接受IPG患者的71%）的SNM功能良好。疼痛采用数字评分量表（NRS）评估，从中位值7.4（3.6 - 10）降至2.3（0 - 6.5）。
当标准治疗不足时，SNM可能是治疗子宫内膜异位症相关性慢性盆腔疼痛的一个好选择。
