Pesciatini F, Cefis M, Lazzaroni A, Pansera P, Cerri B
Int J Clin Pharmacol Res. 1985;5(3):199-204.
The first approach to treatment of dyslipidaemia is with diet. Currently, modified soybean protein is often included in the diet. A study was made of 32 patients with types IIa and IIb dyslipidaemia to see what changes in blood lipids could be induced by a simple low fat diet and a diet with modified soybean protein substituted for part of the animal protein. After six weeks on the initial low fat diet, all of the patients had lower total cholesterol and triglyceride levels, but there were no significant changes in the high density lipoprotein-cholesterol levels. The same diet was continued for eight weeks by 19 of the patients, who continued to improve. The 13 patients who had shown the least response to the initial simple low protein diet were given a diet in which the animal protein was partially replaced with modified soybean protein. This diet further decreased the total cholesterol.
血脂异常的首要治疗方法是饮食疗法。目前,饮食中常包含改性大豆蛋白。对32例IIa型和IIb型血脂异常患者进行了一项研究,以观察简单低脂饮食以及用改性大豆蛋白替代部分动物蛋白的饮食会引起血脂哪些变化。在最初的低脂饮食六周后,所有患者的总胆固醇和甘油三酯水平均降低,但高密度脂蛋白胆固醇水平无显著变化。19例患者继续维持相同饮食八周,病情持续改善。对最初简单低蛋白饮食反应最小的13例患者,给予用改性大豆蛋白部分替代动物蛋白的饮食。这种饮食进一步降低了总胆固醇。