Muzaffar Muhammad Moiz, Samani Syahin, Van Der Velde Peter
Paediatrics, Worcestershire Acute Hospitals NHS Trust, Worcester, GBR.
Cureus. 2025 Mar 6;17(3):e80170. doi: 10.7759/cureus.80170. eCollection 2025 Mar.
The reported incidence of Group A (GAS) bacteraemia is generally low, though it remains a significant concern. We report the case of a three-week-old neonate who presented with blackish discolouration of her toes and a rash, later diagnosed with invasive GAS septicaemia and septic emboli. She received antibiotics and anticoagulation, showing significant improvement, with mild residual hyperpigmentation and minor tissue loss at the two-month follow-up. Our case report highlights that early recognition and treatment of neonatal sepsis, including rare presentations such as septic emboli from pathogens like GAS, are critical for preventing severe complications and ensuring favourable long-term outcomes.
虽然A组（A群链球菌，GAS）菌血症的报告发病率通常较低，但它仍然是一个重大问题。我们报告了一例三周大的新生儿病例，该患儿出现脚趾发黑和皮疹，后来被诊断为侵袭性A群链球菌败血症和脓毒性栓子。她接受了抗生素和抗凝治疗，病情显著改善，在两个月的随访中仅有轻度残留色素沉着和轻微组织损失。我们的病例报告强调，早期识别和治疗新生儿败血症，包括像A群链球菌等病原体引起的脓毒性栓子等罕见表现，对于预防严重并发症和确保良好的长期预后至关重要。
