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心理测量肝性脑病评分(PHES)——何时、如何、为何以及为何不适用:给新手的指南

Psychometric hepatic encephalopathy score (PHES) - when, how, why, and why not: a guide for the unfamiliar.

作者信息

Mumdzhiev Nikola, Tenev Rumen V, Radicheva Mariana P

机构信息

Gastroenterology Department, UMHAT "Prof. Stoyan Kirkovitch", Stara Zagora, Bulgaria.

出版信息

Prz Gastroenterol. 2025;20(1):31-35. doi: 10.5114/pg.2024.145382. Epub 2024 Dec 2.

Abstract

Psychometric hepatic encephalopathy score (PHES) has established itself as one of the most used tests for detecting minimal hepatic encephalopathy. To use it in a certain population one needs to determine what the norms are, and have a proper set of inclusion and especially exclusion criteria. When performing the test (either for validating or as a search tool) authors may benefit from a little guidance. All the 5 tests - DST (Digital Symbol test), Number Connection Test A (NCT A), Number Connection Test B (NCT B), Serial Dotting Test (SDT), Line Drawing Test (LDT) - have certain parameters to follow. In time, deviations have appeared, and comparability between different samples has become somehow limited. As new tests are emerging, and in order to compare, one must be familiar with the tests' variants, benefits, and limitations.

摘要

心理测量肝性脑病评分(PHES)已成为检测轻微肝性脑病最常用的测试之一。要在特定人群中使用该评分,需要确定其正常范围,并制定一套合适的纳入标准,尤其是排除标准。在进行该测试时(无论是用于验证还是作为一种筛查工具),作者可能会从一些指导中受益。所有这五项测试——数字符号试验(DST)、数字连接试验A(NCT A)、数字连接试验B(NCT B)、连续打点试验(SDT)、划线试验(LDT)——都有特定的参数需要遵循。随着时间的推移,出现了偏差,不同样本之间的可比性在某种程度上受到了限制。随着新测试的出现,为了进行比较,必须熟悉这些测试的变体、优点和局限性。

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EASL Clinical Practice Guidelines on the management of hepatic encephalopathy.EASL 临床实践指南:肝性脑病管理。
J Hepatol. 2022 Sep;77(3):807-824. doi: 10.1016/j.jhep.2022.06.001. Epub 2022 Jun 17.

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