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炎症性肠病患者的结构化运动:文献综述

Structured exercise in patients with inflammatory bowel disease: a literature review.

作者信息

Achtenberg Magdalena, Cibor Dorota, Zwolińska-Wcisło Małgorzata

机构信息

Department of Gastroenterology and Hepatology, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.

出版信息

Prz Gastroenterol. 2025;20(1):36-40. doi: 10.5114/pg.2025.148473. Epub 2025 Mar 16.

DOI:10.5114/pg.2025.148473
PMID:40191507
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11966504/
Abstract

Many patients with inflammatory bowel disease (IBD) either do not respond or lose response to dedicated pharmacotherapy; therefore, physical exercise is gaining attention as a potential treatment adjunct. Recent research has highlighted the favorable relationship between physical activity and patient-reported outcomes. The reviewed studies suggest that structured exercise programs are safe and effective in the management of IBD. Yet the benefits of training trials need to be interpreted with caution due to the heterogeneity of the study methods and interventions, small sample sizes, and the absence of long-term follow-ups.

摘要

许多炎症性肠病(IBD)患者对专门的药物治疗没有反应或失去反应;因此,体育锻炼作为一种潜在的治疗辅助手段正受到关注。最近的研究突出了身体活动与患者报告结果之间的良好关系。综述的研究表明,结构化运动计划在IBD的管理中是安全有效的。然而,由于研究方法和干预措施的异质性、样本量小以及缺乏长期随访,训练试验的益处需要谨慎解读。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c19c/11966504/d6995d525549/PG-20-55744-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c19c/11966504/d6995d525549/PG-20-55744-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c19c/11966504/d6995d525549/PG-20-55744-g001.jpg

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本文引用的文献

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Lifestyle, behaviour, and environmental modification for the management of patients with inflammatory bowel diseases: an International Organization for Study of Inflammatory Bowel Diseases consensus.生活方式、行为和环境改变在炎症性肠病患者管理中的作用:国际炎症性肠病组织共识。
Lancet Gastroenterol Hepatol. 2022 Jul;7(7):666-678. doi: 10.1016/S2468-1253(22)00021-8. Epub 2022 Apr 27.
2
Refractory neutrophils and monocytes in patients with inflammatory bowel disease after repeated bouts of prolonged exercise.反复发作性长时间运动后炎症性肠病患者的难治性中性粒细胞和单核细胞。
Cytometry B Clin Cytom. 2021 Nov;100(6):676-682. doi: 10.1002/cyto.b.21996. Epub 2021 Mar 8.
3
Repeated prolonged moderate-intensity walking exercise does not appear to have harmful effects on inflammatory markers in patients with inflammatory bowel disease.
重复进行长时间的中等强度步行运动似乎对炎症性肠病患者的炎症标志物没有不良影响。
Scand J Gastroenterol. 2021 Jan;56(1):30-37. doi: 10.1080/00365521.2020.1845791. Epub 2020 Nov 19.
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Effect of resistance exercise training on Crohn's disease patients.抗阻运动训练对克罗恩病患者的影响。
Intest Res. 2021 Jul;19(3):275-281. doi: 10.5217/ir.2020.00043. Epub 2020 Nov 20.
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Randomised clinical trial: combined impact and resistance training in adults with stable Crohn's disease.随机临床试验:稳定期克罗恩病成人的联合冲击和抗阻训练。
Aliment Pharmacol Ther. 2020 Sep;52(6):964-975. doi: 10.1111/apt.16002. Epub 2020 Jul 30.
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Moderate endurance and muscle training is beneficial and safe in patients with quiescent or mildly active Crohn's disease.中强度耐力和肌肉训练对处于缓解期或轻度活动期的克罗恩病患者有益且安全。
United European Gastroenterol J. 2020 Aug;8(7):804-813. doi: 10.1177/2050640620936383. Epub 2020 Jun 25.
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Improvement of Fatigue and Quality of Life in Patients with Quiescent Inflammatory Bowel Disease Following a Personalized Exercise Program.个性化运动方案对缓解静止期炎症性肠病患者疲劳和提高生活质量的作用
Dig Dis Sci. 2021 Feb;66(2):597-604. doi: 10.1007/s10620-020-06222-5. Epub 2020 Apr 1.
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Real-world Pattern of Biologic Use in Patients With Inflammatory Bowel Disease: Treatment Persistence, Switching, and Importance of Concurrent Immunosuppressive Therapy.真实世界中炎症性肠病患者的生物制剂使用模式:治疗持久性、转换及同时应用免疫抑制治疗的重要性。
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