Sun Haitao, Zhang Qi, Xu Kehan, Zhou Zihuan, Jiang Dongjie, He Shaohui, Liu Jilu, Wei Haifeng
Department of Spinal Tumor, Changzheng Hospital, Naval Medical University CN, Shanghai, China.
Department of Spinal Surgery, Naval Hospital of Eastern Theater, Zhoushan, China.
PeerJ. 2025 Apr 3;13:e19076. doi: 10.7717/peerj.19076. eCollection 2025.
Unilateral biportal endoscopy (UBE) has been developing rapidly in coincidence with the popularization of minimally invasive spine surgery (MISS). However, the clinical outcome and invasiveness of UBE-assisted spinal surgery (UBESS) are undefined. The aim of the present study was to summarize the clinical outcome and surgical invasiveness of UBE for the treatment of various spinal degenerative diseases in a single center to validate the safety and application value of UBESS.
Included in this study were 105 patients who received UBESS from November 2021 to June 2022 in our center. All patients were followed up postoperatively for at least 12 months. All basic information was recorded to depict the demographic and surgical variables. Clinical outcomes were assessed in terms of the operation time, complications, days of hospital stay, total blood loss, intraoperative blood loss, postoperative drainage volume, hidden blood loss, biochemical changes associated with surgical injury, comparison of the visual analogue scale (VAS) for back and leg pain, Japanese Orthopedic Association (JOA) scores for cervical diseases at preoperative and postoperative stage, as well as Oswetry Disability Index (ODI), and modified MacNab scores one year after treatment.
Of the 105 included patients, 68 patients were with single-level lumbar degenerative diseases, 22 with two-level diseases, two with three-level diseases, 10 with single-level isthmic spondylolisthesis, and three with single-level cervical spondylotic radiculopathy. UBE was performed by using five surgical approaches. The operation time, days of hospital stay, blood loss, postoperative immobilization time and prognosis were all estimated in consideration of the surgical approaches and the number of operated segments. The mean operation time ranged from 80 min to 214 min for single-level spinal diseases, and 112 min to 330 min for two-level ones. Total blood loss was higher in multilevel spinal surgery and single-level UBE-assisted lumbar interbody fusion+discectomy (ULIFD). The postoperative immobilization duration was between 0.5 and 2 days for single level spinal diseases, 1 and 3 days for 2-level diseases, fewer than 2 days for three-level diseases, and 1.5-12 days for isthmic spondylolisthesis (IS). The VAS and ODI for lumbar diseases decreased significantly and the JOA scores for cervical diseases improved after operation. The satisfaction rate was 89.70%, 85.71%, 90.00%, 66.67%, and 90.00% for the five surgical approaches respectively.
UBESS has proved to be a safe, reliable and minimally invasive option for spinal degenerative diseases, with significant benefits of pain control, rapid functional recovery, short hospitalization, and early rehabilitation. However, postoperative hidden blood loss should be put under the careful management when performing UBESS.
随着微创脊柱手术(MISS)的普及,单侧双通道内镜技术(UBE)发展迅速。然而,UBE辅助脊柱手术(UBESS)的临床疗效和侵袭性尚不明确。本研究旨在总结单中心UBE治疗各种脊柱退行性疾病的临床疗效和手术侵袭性,以验证UBESS的安全性和应用价值。
本研究纳入了2021年11月至2022年6月在我院接受UBESS治疗的105例患者。所有患者术后均接受至少12个月的随访。记录所有基本信息以描述人口统计学和手术变量。从手术时间、并发症、住院天数、总失血量、术中失血量、术后引流量、隐性失血量、与手术损伤相关的生化变化、腰腿痛视觉模拟量表(VAS)比较、术前和术后颈椎疾病的日本骨科协会(JOA)评分、Oswestry功能障碍指数(ODI)以及治疗后一年的改良MacNab评分等方面评估临床疗效。
105例纳入患者中,68例为单节段腰椎退行性疾病,22例为双节段疾病,2例为三节段疾病,10例为单节段峡部裂型腰椎滑脱,3例为单节段神经根型颈椎病。采用五种手术入路进行UBE手术。根据手术入路和手术节段数量对手术时间、住院天数、失血量、术后固定时间和预后进行评估。单节段脊柱疾病的平均手术时间为80分钟至214分钟,双节段疾病为112分钟至330分钟。多节段脊柱手术和单节段UBE辅助腰椎椎间融合+椎间盘切除术(ULIFD)的总失血量较高。单节段脊柱疾病的术后固定时间为0.5至2天,双节段疾病为1至3天,三节段疾病少于2天,峡部裂型腰椎滑脱(IS)为1.5至12天。术后腰椎疾病的VAS和ODI显著降低,颈椎疾病的JOA评分提高。五种手术入路的满意率分别为89.70%、85.71%、90.00%、66.67%和90.00%。
UBESS已被证明是治疗脊柱退行性疾病的一种安全、可靠且微创的选择,在控制疼痛、快速功能恢复、缩短住院时间和早期康复方面具有显著优势。然而,在进行UBESS时,应仔细管理术后隐性失血。