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对蓟罂粟的植物化学和植物药理学见解:印度东部地区作为民间药物的综合研究方法

Phytochemical and Phytopharmacological Insights into Argemone mexicana: Integrative Approaches in Eastern Indian Region as Folk Medicine.

作者信息

Kumar Dharmendra, Singh Laliteshwar Pratap, Chatterjee Sandip

机构信息

Narayan Institute of Pharmacy, Gopal Narayan Singh University, Sasaram, Bihar, India.

出版信息

Curr Drug Res Rev. 2025 Apr 4. doi: 10.2174/0125899775362872250319082142.

Abstract

INTRODUCTION

Argemone mexicana, commonly known as the Mexican poppy, has earned significant recognition in the traditional healing systems of the Eastern Indian region, where it has been used for centuries as a folk remedy for a variety of diseases. The study was based on search or identified through Pubmed, Google Scholar, Science Direct, etc. Meta-analysis: Phytochemical analysis has demonstrated that the alkaloids present in A. mexicana exhibit potent antimicrobial properties, making the plant an effective natural remedy for treating infections caused by bacteria, fungi, and viruses. In addition, the plant's flavonoids and phenolic compounds are recognized for their strong anti-inflammatory and antioxidant activities, which play a crucial role in alleviating pain, reducing inflammation, and promoting tissue repair. Furthermore, A. mexicana has shown significant analgesic effects, which support its traditional use as a pain reliever. The integration of ethnobotanical knowledge with modern pharmacological research is essential for fully unlocking the therapeutic potential of A. mexicana. Future Scope: Future studies must focus on comprehensive clinical trials, toxicological evaluations, and in-depth mechanistic investigations to validate the efficacy and safety of A. mexicana in human populations.

CONCLUSION

This review highlights the urgent need for further research to bridge the gap between traditional knowledge and contemporary scientific understanding. By advancing the study of A. mexicana, there is a significant opportunity to develop novel, cost-effective, and sustainable therapeutic agents that could serve as alternatives to synthetic drugs, particularly in regions where access to modern healthcare is limited.

摘要

引言

蓟罂粟,俗称墨西哥罂粟,在印度东部地区的传统治疗体系中已获得显著认可,在那里它作为治疗多种疾病的民间药物已被使用了几个世纪。该研究基于通过PubMed、谷歌学术、科学Direct等进行的搜索或识别。荟萃分析:植物化学分析表明,蓟罂粟中存在的生物碱具有强大的抗菌特性,使该植物成为治疗由细菌、真菌和病毒引起的感染的有效天然药物。此外,该植物的黄酮类化合物和酚类化合物因其强大的抗炎和抗氧化活性而闻名,这些活性在减轻疼痛、减轻炎症和促进组织修复方面发挥着关键作用。此外,蓟罂粟已显示出显著的镇痛作用,这支持了其作为止痛药的传统用途。将民族植物学知识与现代药理学研究相结合对于充分挖掘蓟罂粟的治疗潜力至关重要。未来展望:未来的研究必须集中在全面的临床试验、毒理学评估和深入的机制研究上,以验证蓟罂粟在人类群体中的疗效和安全性。

结论

本综述强调迫切需要进一步研究,以弥合传统知识与当代科学理解之间的差距。通过推进对蓟罂粟的研究,有重大机会开发新型、经济高效且可持续的治疗药物,这些药物可作为合成药物的替代品,特别是在获得现代医疗保健有限的地区。

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